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3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk

BACKGROUND: Genome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified variants lie in non-coding regions, limiting the id...

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Detalles Bibliográficos
Autores principales:	Liu, Ning, Sadlon, Timothy, Wong, Ying Y., Pederson, Stephen, Breen, James, Barry, Simon C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244893/ https://www.ncbi.nlm.nih.gov/pubmed/35773720 http://dx.doi.org/10.1186/s13072-022-00456-5

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