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Apoferritin-Encapsulated Jerantinine A for Transferrin Receptor Targeting and Enhanced Selectivity in Breast Cancer Therapy

[Image: see text] The O-acetyl (or acetate) derivative of the Aspidosperma alkaloid Jerantinine A (JAa) elicits anti-tumor activity against cancer cell lines including mammary carcinoma cell lines irrespective of receptor status (0.14 < GI(50) < 0.38 μM), targeting microtubule dynamics. By exp...

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Detalles Bibliográficos
Autores principales:	Abuzaid, Haneen, Abdelrazig, Salah, Ferreira, Lenny, Collins, Hilary M., Kim, Dong-Hyun, Lim, Kuan-Hon, Kam, Toh-Seok, Turyanska, Lyudmila, Bradshaw, Tracey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244903/ https://www.ncbi.nlm.nih.gov/pubmed/35785302 http://dx.doi.org/10.1021/acsomega.2c00997

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