Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions

[Image: see text] A novel TEA-catalyzed sugar-esterification of phosphinic acids was used as a general and efficient approach for the synthesis of a variety of phosphinates without any transition metal. The high efficiency of the current methodology and a convenient experimental procedure compensate...

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Autores principales: Abdou, Moaz M., O’Neill, Paul M., Amigues, Eric, Matziari, Magdalini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244928/
https://www.ncbi.nlm.nih.gov/pubmed/35785277
http://dx.doi.org/10.1021/acsomega.2c00712
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author Abdou, Moaz M.
O’Neill, Paul M.
Amigues, Eric
Matziari, Magdalini
author_facet Abdou, Moaz M.
O’Neill, Paul M.
Amigues, Eric
Matziari, Magdalini
author_sort Abdou, Moaz M.
collection PubMed
description [Image: see text] A novel TEA-catalyzed sugar-esterification of phosphinic acids was used as a general and efficient approach for the synthesis of a variety of phosphinates without any transition metal. The high efficiency of the current methodology and a convenient experimental procedure compensate for the moderate yields obtained. Another advantage is that the reaction tolerates different substituents attached to the phosphinic acids and the sugar moieties alongside the ease of isolation of the product.
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spelling pubmed-92449282022-07-01 Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions Abdou, Moaz M. O’Neill, Paul M. Amigues, Eric Matziari, Magdalini ACS Omega [Image: see text] A novel TEA-catalyzed sugar-esterification of phosphinic acids was used as a general and efficient approach for the synthesis of a variety of phosphinates without any transition metal. The high efficiency of the current methodology and a convenient experimental procedure compensate for the moderate yields obtained. Another advantage is that the reaction tolerates different substituents attached to the phosphinic acids and the sugar moieties alongside the ease of isolation of the product. American Chemical Society 2022-06-16 /pmc/articles/PMC9244928/ /pubmed/35785277 http://dx.doi.org/10.1021/acsomega.2c00712 Text en © 2022 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by-nc-nd/4.0/Permits non-commercial access and re-use, provided that author attribution and integrity are maintained; but does not permit creation of adaptations or other derivative works (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Abdou, Moaz M.
O’Neill, Paul M.
Amigues, Eric
Matziari, Magdalini
Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title_full Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title_fullStr Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title_full_unstemmed Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title_short Unprecedented Convergent Synthesis of Sugar-Functionalization of Phosphinic Acids under Metal-Free Conditions
title_sort unprecedented convergent synthesis of sugar-functionalization of phosphinic acids under metal-free conditions
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244928/
https://www.ncbi.nlm.nih.gov/pubmed/35785277
http://dx.doi.org/10.1021/acsomega.2c00712
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