Molecular docking of DS-3032B, a mouse double minute 2 enzyme antagonist with potential for oncology treatment development

BACKGROUND: It is known that p53 suppression is an important marker of poor prognosis of cancers, especially in solid tumors of the breast, lung, stomach, and esophagus; liposarcomas, glioblastomas, and leukemias. Because p53 has mouse double minute 2 (MDM2) as its primary negative regulator, this m...

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Detalles Bibliográficos
Autores principales: da Mota, Vítor Hugo Sales, Freire de Melo, Fabrício, de Brito, Breno Bittencourt, da Silva, Filipe Antônio França, Teixeira, Kádima Nayara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244969/
https://www.ncbi.nlm.nih.gov/pubmed/35949428
http://dx.doi.org/10.5306/wjco.v13.i6.496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9244969/
https://www.ncbi.nlm.nih.gov/pubmed/35949428
http://dx.doi.org/10.5306/wjco.v13.i6.496

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