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Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
Epstein-Barr virus (EBV) is a cancer-associated pathogen responsible for 165,000 deaths annually. EBV is also the etiological agent of infectious mononucleosis and is linked to multiple sclerosis and rheumatoid arthritis. Thus, an EBV vaccine would have a significant global health impact. EBV is ora...
Autores principales: | Malhi, Harman, Homad, Leah J., Wan, Yu-Hsin, Poudel, Bibhav, Fiala, Brooke, Borst, Andrew J., Wang, Jing Yang, Walkey, Carl, Price, Jason, Wall, Abigail, Singh, Suruchi, Moodie, Zoe, Carter, Lauren, Handa, Simran, Correnti, Colin E., Stoddard, Barry L., Veesler, David, Pancera, Marie, Olson, James, King, Neil P., McGuire, Andrew T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245003/ https://www.ncbi.nlm.nih.gov/pubmed/35705092 http://dx.doi.org/10.1016/j.xcrm.2022.100658 |
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