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In Vitro Identification of Potential Metabolites of Plinabulin (NPI 2358) in Hepatic Preparations Using Liquid Chromatography–Ion Trap Mass Spectrometry

[Image: see text] Plinabulin (1, NPI2358), a vascular disrupting agent (VDA) molecule, is a synthetic analogue of the natural product phenylahistin (2, NPI 2350), which is isolated from Aspergillus ustus. Evaluation of the in vitro metabolic profile of VDA plinabulin using human liver microsomes (HL...

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Detalles Bibliográficos
Autores principales:	Al-Shakliah, Nasser S., Kadi, Adnan A., Al-Salahi, Rashad, Rahman, A. F. M. Motiur
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245099/ https://www.ncbi.nlm.nih.gov/pubmed/35785266 http://dx.doi.org/10.1021/acsomega.2c00929

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