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Generation of a homozygous mutant drug transporter (ABCB1) knockout line in the sea urchin Lytechinus pictus

Sea urchins are premier model organisms for the study of early development. However, the lengthy generation times of commonly used species have precluded application of stable genetic approaches. Here, we use the painted sea urchin Lytechinus pictus to address this limitation and to generate a homoz...

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Detalles Bibliográficos
Autores principales: Vyas, Himanshu, Schrankel, Catherine S., Espinoza, Jose A., Mitchell, Kasey L., Nesbit, Katherine T., Jackson, Elliot, Chang, Nathan, Lee, Yoon, Warner, Jacob, Reitzel, Adam, Lyons, Deirdre C., Hamdoun, Amro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245184/
https://www.ncbi.nlm.nih.gov/pubmed/35666622
http://dx.doi.org/10.1242/dev.200644

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