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Generation of a homozygous mutant drug transporter (ABCB1) knockout line in the sea urchin Lytechinus pictus
Sea urchins are premier model organisms for the study of early development. However, the lengthy generation times of commonly used species have precluded application of stable genetic approaches. Here, we use the painted sea urchin Lytechinus pictus to address this limitation and to generate a homoz...
Autores principales: | Vyas, Himanshu, Schrankel, Catherine S., Espinoza, Jose A., Mitchell, Kasey L., Nesbit, Katherine T., Jackson, Elliot, Chang, Nathan, Lee, Yoon, Warner, Jacob, Reitzel, Adam, Lyons, Deirdre C., Hamdoun, Amro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245184/ https://www.ncbi.nlm.nih.gov/pubmed/35666622 http://dx.doi.org/10.1242/dev.200644 |
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