Upregulation of CCT3 predicts poor prognosis and promotes cell proliferation via inhibition of ferroptosis and activation of AKT signaling in lung adenocarcinoma

BACKGROUND: Chaperonin containing TCP1 subunit 3 (CCT3) acts as an oncogene in cancers, whereas its role and underlying mechanisms in lung adenocarcinoma (LUAD) are poorly understood. This study investigated the clinical relevance and function of CCT3 in LUAD. METHODS: Clinical relevance of CCT3 in...

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Detalles Bibliográficos
Autores principales: Wang, Kun, He, Jian, Tu, Changling, Xu, Hui, Zhang, Xugang, Lv, Yongchang, Song, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245217/
https://www.ncbi.nlm.nih.gov/pubmed/35773623
http://dx.doi.org/10.1186/s12860-022-00424-7

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