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Brain microvascular endothelial cell dysfunction in an isogenic juvenile iPSC model of Huntington’s disease

Huntington’s disease (HD) is an inherited neurodegenerative disease caused by expansion of cytosine–adenine–guanine (CAG) repeats in the huntingtin gene, which leads to neuronal loss and decline in cognitive and motor function. Increasing evidence suggests that blood–brain barrier (BBB) dysfunction...

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Detalles Bibliográficos
Autores principales:	Linville, Raleigh M., Nerenberg, Renée F., Grifno, Gabrielle, Arevalo, Diego, Guo, Zhaobin, Searson, Peter C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245306/ https://www.ncbi.nlm.nih.gov/pubmed/35773691 http://dx.doi.org/10.1186/s12987-022-00347-7

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