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Subsets of Tissue CD4 T Cells Display Different Susceptibilities to HIV Infection and Death: Analysis by CyTOF and Single Cell RNA-seq

CD4 T lymphocytes belong to diverse cellular subsets whose sensitivity or resistance to HIV-associated killing remains to be defined. Working with lymphoid cells from human tonsils, we characterized the HIV-associated depletion of various CD4 T cell subsets using mass cytometry and single-cell RNA-s...

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Detalles Bibliográficos
Autores principales: Luo, Xiaoyu, Frouard, Julie, Zhang, Gang, Neidleman, Jason, Xie, Guorui, Sheedy, Emma, Roan, Nadia R., Greene, Warner C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245423/
https://www.ncbi.nlm.nih.gov/pubmed/35784348
http://dx.doi.org/10.3389/fimmu.2022.883420

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