Cargando…

In-Line Monitoring of Downstream Purification Processes for VSV Based SARS-CoV-2 Vaccine Using a Novel Technique

The COVID-19 pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) increases the need for a rapid development of efficient vaccines. Among other vaccines in clinical trials, a recombinant VSV-∆G-spike vaccine was developed by the Israel Institute for Biological Research (II...

Descripción completa

Detalles Bibliográficos
Autores principales:	Makovitzki, Arik, Jayson, Avital, Oren, Ziv, Lerer, Elad, Kafri, Yaron, Dor, Eyal, Cherry, Lilach, Tzadok, Hanan, Levin, Lilach, Hazan, Ophir, Simon, Irit, Tal, Arnon, Girshengorn, Meni, Rosen, Osnat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245488/ https://www.ncbi.nlm.nih.gov/pubmed/35822799 http://dx.doi.org/10.3390/biotech10040025

Ejemplares similares

Evaluation of a downstream process for the recovery and concentration of a Cell-Culture-Derived rVSV-Spike COVID-19 vaccine candidate
por: Makovitzki, Arik, et al.
Publicado: (2021)

Highly Efficient Purification of Recombinant VSV-∆G-Spike Vaccine against SARS-CoV-2 by Flow-Through Chromatography
por: Lerer, Elad, et al.
Publicado: (2021)

Optimization of VSV‐ΔG‐spike production process with the Ambr15 system for a SARS‐COV‐2 vaccine
por: Rosen, Osnat, et al.
Publicado: (2022)

Application of Ambr15 system for simulation of entire SARS‐CoV‐2 vaccine production process involving macrocarriers
por: Jayson, Avital, et al.
Publicado: (2022)

SARS-CoV-2 spike antigen quantification by targeted mass spectrometry of a virus-based vaccine
por: Rosen, Osnat, et al.
Publicado: (2022)

Virus Inactivation in Water Using Laser-Induced Graphene Filters
por: Barbhuiya, Najmul Haque, et al.
Publicado: (2021)

Highly Specific Monoclonal Antibody Targeting the Botulinum Neurotoxin Type E Exposed SNAP-25 Neoepitope
por: Mechaly, Adva, et al.
Publicado: (2022)

Cannabis, One Health, and Veterinary Medicine: Cannabinoids’ Role in Public Health, Food Safety, and Translational Medicine
por: Ritter, Sivan, et al.
Publicado: (2020)

Identification of SARS-CoV-2 Receptor Binding Inhibitors by In Vitro Screening of Drug Libraries
por: David, Alon Ben, et al.
Publicado: (2021)

A single dose of recombinant VSV-∆G-spike vaccine provides protection against SARS-CoV-2 challenge
por: Yahalom-Ronen, Yfat, et al.
Publicado: (2020)

Thermophilic Filamentous Fungus C1-Cell-Cloned SARS-CoV-2-Spike-RBD-Subunit-Vaccine Adjuvanted with Aldydrogel(®)85 Protects K18-hACE2 Mice against Lethal Virus Challenge
por: Nechooshtan, Ram, et al.
Publicado: (2022)

Studying the differential efficacy of postsymptom antitoxin treatment in type A versus type B botulism using a rabbit spirometry model
por: Torgeman, Amram, et al.
Publicado: (2018)

A Rabbit Model for Prolonged Continuous Intravenous Infusion Via a Peripherally Inserted Central Catheter
por: Dor, Eyal, et al.
Publicado: (2021)

Rapid Induction of Protective Immunity against Pneumonic Plague by Yersinia pestis Polymeric F1 and LcrV Antigens
por: Aftalion, Moshe, et al.
Publicado: (2023)

Role of Homologous Fc Fragment in the Potency and Efficacy of Anti-Botulinum Antibody Preparations
por: Torgeman, Amram, et al.
Publicado: (2017)

VSV-ΔG-Spike Candidate Vaccine Induces Protective Immunity and Protects K18-hACE2 Mice against SARS-CoV-2 Variants
por: Yahalom-Ronen, Yfat, et al.
Publicado: (2023)

Phage Therapy Potentiates Second-Line Antibiotic Treatment against Pneumonic Plague
por: Vagima, Yaron, et al.
Publicado: (2022)

Immunologic and Protective Properties of Subunit- vs. Whole Toxoid-Derived Anti-Botulinum Equine Antitoxin
por: Ben David, Alon, et al.
Publicado: (2022)

Insights from the Infection Cycle of VSV-ΔG-Spike Virus
por: Milrot, Elad, et al.
Publicado: (2022)

Magnetic resonance-guided focused ultrasound treatment of facet joint pain: summary of preclinical phase
por: Harnof, Sagi, et al.
Publicado: (2014)

Post-Exposure Anti-Ricin Treatment Protects Swine against Lethal Systemic and Pulmonary Exposures
por: Falach, Reut, et al.
Publicado: (2020)

Comparing in-lab full polysomnography for diagnosing sleep apnea in children to home sleep apnea tests (HSAT) with an online video attending technician
por: Green, Amit, et al.
Publicado: (2022)

rVSV-ΔG-SARS-CoV-2-S vaccine: repeated intramuscular (IM) toxicity, local tolerance, immunogenicity and biodistribution study in NZW rabbits
por: Rosner, Amir, et al.
Publicado: (2022)

A phenomenological exploration of work-related post-traumatic growth among high-functioning adults maltreated as children
por: Kaye-Tzadok, Avital, et al.
Publicado: (2022)

Tyrosine kinase inhibitors induced immune thrombocytopenia in chronic myeloid leukemia?
por: Barak, Avital F., et al.
Publicado: (2011)

Acute and Long-Term Effects of an Internet-Based, Self-Help Comprehensive Behavioral Intervention for Children and Teens with Tic Disorders with Comorbid Attention Deficit Hyperactivity Disorder, or Obsessive Compulsive Disorder: A Reanalysis of Data from a Randomized Controlled Trial
por: Rachamim, Lilach, et al.
Publicado: (2021)

Detectable Vesicular Stomatitis Virus (VSV)–Specific Humoral and Cellular Immune Responses Following VSV–Ebola Virus Vaccination in Humans
por: Poetsch, Joseph H, et al.
Publicado: (2019)

Feline cognitive dysfunction as a model for Alzheimer’s disease in the research of CBD as a potential treatment—a narrative review
por: Zadik-Weiss, Lilach, et al.
Publicado: (2020)

Internet-based guided self-help comprehensive behavioral intervention for tics (ICBIT) for youth with tic disorders: a feasibility and effectiveness study with 6 month-follow-up
por: Rachamim, Lilach, et al.
Publicado: (2020)

A Rabbit Model for the Evaluation of Drugs for Treating the Chronic Phase of Botulism
por: Torgeman, Amram, et al.
Publicado: (2021)

Development and Applications of VSV Vectors Based on Cell Tropism
por: Tani, Hideki, et al.
Publicado: (2012)

Titration methods for rVSV-based vaccine manufacturing
por: Gélinas, Jean-François, et al.
Publicado: (2020)

Human Transcriptomic Response to the VSV-Vectored Ebola Vaccine
por: Santoro, Francesco, et al.
Publicado: (2021)

Dissecting Dynamic Genetic Variation That Controls Temporal Gene Response in Yeast
por: Brodt, Avital, et al.
Publicado: (2014)

Lost in the matrix: Dialectical tensions in facilitating virtual video groups during COVID-19 pandemic
por: Ben-David, Yael, et al.
Publicado: (2021)

Guess What We Can Hear – Novel Voice Biomarkers for the Remote Detection of Disease
por: Singh Sara, Jaskanwal Deep, et al.
Publicado: (2023)

Development and Validation of an Innovative Analytical Approach for the Quantitation of Tris(Hydroxymethyl)Aminomethane (TRIS) in Pharmaceutical Formulations by Liquid Chromatography Tandem Mass Spectrometry
por: Madmon, Moran, et al.
Publicado: (2022)

Assessing the impact of a knowledge translation intervention on physical therapists’ self-efficacy and implementation of motor learning practice
por: Kafri, Michal, et al.
Publicado: (2023)

Market mechanisms' distortions of higher education: Punjabi international students in Canada
por: Marom, Lilach
Publicado: (2022)

Distinct structural rearrangements of the VSV glycoprotein drive membrane fusion
por: Libersou, Sonia, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_hr0m4q20cse02eh3pncfgl6k6f