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Molecular and Functional Analyses of the Primordial Costimulatory Molecule CD80/86 and Its Receptors CD28 and CD152 (CTLA-4) in a Teleost Fish

The moderate activation of T cells in mammals requires the costimulatory molecules, CD80 and CD86, on antigen-presenting cells to interact with their respective T cell receptors, CD28 and CD152 (CTLA-4), to promote costimulatory signals. In contrast, teleost fish (except salmonids) only possess CD80...

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Detalles Bibliográficos
Autores principales:	Lu, Tao-Zhen, Liu, Xun, Wu, Chang-Song, Ma, Zi-You, Wang, Yang, Zhang, Yong-An, Zhang, Xu-Jie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245511/ https://www.ncbi.nlm.nih.gov/pubmed/35784316 http://dx.doi.org/10.3389/fimmu.2022.885005

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