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Histopathological and immunological spectrum in response evaluation of talimogene laherparepvec treatment and correlation with durable response in patients with cutaneous melanoma

Talimogene laherparepvec (T-VEC) is an intralesional oncolytic virotherapy for patients with irresectable stage III–IVM1a cutaneous melanoma. Although this treatment is considered to mainly act through T cell-mediated mechanisms, prominent numbers of plasma cells after T-VEC treatment have been desc...

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Detalles Bibliográficos
Autores principales: Mulder, Evalyn E.A.P., Damman, Jeffrey, Verver, Daniëlle, van der Veldt, Astrid A.M., Tas, Sam, Khemai-Mehraban, Tamana, Heezen, Kim C., Wouters, Roxane A., Verhoef, Cornelis, Verjans, Georges M.G.M., Langerak, Anton W., Grünhagen, Dirk J., Mooyaart, Antien L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245556/
https://www.ncbi.nlm.nih.gov/pubmed/35446267
http://dx.doi.org/10.1097/CMR.0000000000000824