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SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals
BACKGROUND: Endometriosis (EMS), an endocrine-related inflammatory disease, is characterized by estrogen and progesterone imbalance in ectopic lesions. However, its pathogenic mechanism has not been fully elucidated. While SCM-198 is the synthetic form of leonurine and has multiple pharmacological a...
Autores principales: | Lin, Yi-Kong, Li, Yun-Yun, Li, Yue, Li, Da-Jin, Wang, Xiao-Lin, Wang, Li, Yu, Min, Zhu, Yi-Zhun, Cheng, Jia-Jing, Du, Mei-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245568/ https://www.ncbi.nlm.nih.gov/pubmed/35784569 http://dx.doi.org/10.3389/fendo.2022.858176 |
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