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Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease

INTRODUCTION: Parkinson's disease (PD) patients frequently engage in rehabilitation to ameliorate symptoms. During the Coronavirus disease 2019 (COVID-19) pandemic, access to rehabilitation programs has been markedly limited, consequently, telerehabilitation gained popularity. In this prospecti...

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Autores principales: Bianchini, Edoardo, Onelli, Camilla, Morabito, Carmen, Alborghetti, Marika, Rinaldi, Domiziana, Anibaldi, Paolo, Marcolongo, Adriano, Salvetti, Marco, Pontieri, Francesco E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245570/
https://www.ncbi.nlm.nih.gov/pubmed/35785358
http://dx.doi.org/10.3389/fneur.2022.909197
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author Bianchini, Edoardo
Onelli, Camilla
Morabito, Carmen
Alborghetti, Marika
Rinaldi, Domiziana
Anibaldi, Paolo
Marcolongo, Adriano
Salvetti, Marco
Pontieri, Francesco E.
author_facet Bianchini, Edoardo
Onelli, Camilla
Morabito, Carmen
Alborghetti, Marika
Rinaldi, Domiziana
Anibaldi, Paolo
Marcolongo, Adriano
Salvetti, Marco
Pontieri, Francesco E.
author_sort Bianchini, Edoardo
collection PubMed
description INTRODUCTION: Parkinson's disease (PD) patients frequently engage in rehabilitation to ameliorate symptoms. During the Coronavirus disease 2019 (COVID-19) pandemic, access to rehabilitation programs has been markedly limited, consequently, telerehabilitation gained popularity. In this prospective, open-label, and pilot study, we aimed to investigate feasibility, safety, and efficacy of telerehabilitation in mild-to-moderate PD patients. MATERIALS AND METHODS: Twenty-three PD patients, with Hoehn and Yahr stage <3, without gait disturbances or dementia and capable of using the televisit platform, were recruited for a 5-week telerehabilitation program, consisting of 1 remote visit with a therapist and a minimum of two sessions of >30-min of self-conducted exercises per week. Patients received video tutorials of exercises and were asked to keep a diary of sessions. At baseline (T0), at the end of the intervention (T1), and 1 month after the end of treatment (T2), patients were remotely assessed with MDS-UPDRS part I-III, PDQ-39, Functional Independence Measure (FIM), and Frontal Assessment Battery scales, respectively. Acceptable compliance to the program was defined as >60% matching of frequency and duration of sessions, whereas optimal compliance was set at >80% matching. RESULTS: The dropout rate was 0%. Over 85% of patients reached acceptable adherence cut-off and around 70% reached optimal one. No adverse events were reported during sessions. The repeated measure analysis of variance (rANOVA) showed a significant effect of factor “time” for MDS-UPDRS-III (p < 0.0001) with a mean reduction of 4.217 points between T0 and T1 and return to baseline at T2. No significant effect was found for other outcome measures. CONCLUSION: Our findings demonstrate that telerehabilitation is safe, feasible, and effective on motor symptoms in mild-to-moderate PD patients.
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spelling pubmed-92455702022-07-01 Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease Bianchini, Edoardo Onelli, Camilla Morabito, Carmen Alborghetti, Marika Rinaldi, Domiziana Anibaldi, Paolo Marcolongo, Adriano Salvetti, Marco Pontieri, Francesco E. Front Neurol Neurology INTRODUCTION: Parkinson's disease (PD) patients frequently engage in rehabilitation to ameliorate symptoms. During the Coronavirus disease 2019 (COVID-19) pandemic, access to rehabilitation programs has been markedly limited, consequently, telerehabilitation gained popularity. In this prospective, open-label, and pilot study, we aimed to investigate feasibility, safety, and efficacy of telerehabilitation in mild-to-moderate PD patients. MATERIALS AND METHODS: Twenty-three PD patients, with Hoehn and Yahr stage <3, without gait disturbances or dementia and capable of using the televisit platform, were recruited for a 5-week telerehabilitation program, consisting of 1 remote visit with a therapist and a minimum of two sessions of >30-min of self-conducted exercises per week. Patients received video tutorials of exercises and were asked to keep a diary of sessions. At baseline (T0), at the end of the intervention (T1), and 1 month after the end of treatment (T2), patients were remotely assessed with MDS-UPDRS part I-III, PDQ-39, Functional Independence Measure (FIM), and Frontal Assessment Battery scales, respectively. Acceptable compliance to the program was defined as >60% matching of frequency and duration of sessions, whereas optimal compliance was set at >80% matching. RESULTS: The dropout rate was 0%. Over 85% of patients reached acceptable adherence cut-off and around 70% reached optimal one. No adverse events were reported during sessions. The repeated measure analysis of variance (rANOVA) showed a significant effect of factor “time” for MDS-UPDRS-III (p < 0.0001) with a mean reduction of 4.217 points between T0 and T1 and return to baseline at T2. No significant effect was found for other outcome measures. CONCLUSION: Our findings demonstrate that telerehabilitation is safe, feasible, and effective on motor symptoms in mild-to-moderate PD patients. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9245570/ /pubmed/35785358 http://dx.doi.org/10.3389/fneur.2022.909197 Text en Copyright © 2022 Bianchini, Onelli, Morabito, Alborghetti, Rinaldi, Anibaldi, Marcolongo, Salvetti and Pontieri. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neurology
Bianchini, Edoardo
Onelli, Camilla
Morabito, Carmen
Alborghetti, Marika
Rinaldi, Domiziana
Anibaldi, Paolo
Marcolongo, Adriano
Salvetti, Marco
Pontieri, Francesco E.
Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title_full Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title_fullStr Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title_full_unstemmed Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title_short Feasibility, Safety, and Effectiveness of Telerehabilitation in Mild-to-Moderate Parkinson's Disease
title_sort feasibility, safety, and effectiveness of telerehabilitation in mild-to-moderate parkinson's disease
topic Neurology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245570/
https://www.ncbi.nlm.nih.gov/pubmed/35785358
http://dx.doi.org/10.3389/fneur.2022.909197
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