Microbiome-associated human genetic variants impact phenome-wide disease risk

Human genetic variation associates with the composition of the gut microbiome, yet its influence on clinical traits remains largely unknown. We analyzed the consequences of nearly a thousand gut microbiome-associated variants (MAVs) on phenotypes reported in electronic health records from tens of th...

Descripción completa

Detalles Bibliográficos
Autores principales: Markowitz, Robert H. George, LaBella, Abigail Leavitt, Shi, Mingjian, Rokas, Antonis, Capra, John A., Ferguson, Jane F., Mosley, Jonathan D., Bordenstein, Seth R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245617/
https://www.ncbi.nlm.nih.gov/pubmed/35749358
http://dx.doi.org/10.1073/pnas.2200551119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245617/
https://www.ncbi.nlm.nih.gov/pubmed/35749358
http://dx.doi.org/10.1073/pnas.2200551119

Ejemplares similares