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Harnessing anti-cytomegalovirus immunity for local immunotherapy against solid tumors

Tumor infiltration by T cells profoundly affects cancer progression and responses to immunotherapy. However, the tumor immunosuppressive microenvironment can impair the induction, trafficking, and local activity of antitumor T cells. Here, we investigated whether intratumoral injection of virus-deri...

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Detalles Bibliográficos
Autores principales: Çuburu, Nicolas, Bialkowski, Lukasz, Pontejo, Sergio M., Sethi, Shiv K., Bell, Alexander T. F., Kim, Rina, Thompson, Cynthia D., Lowy, Douglas R., Schiller, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245622/
https://www.ncbi.nlm.nih.gov/pubmed/35749366
http://dx.doi.org/10.1073/pnas.2116738119