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Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms

Proper orientation of the mitotic spindle plays a crucial role in embryos, during tissue development, and in adults, where it functions to dissipate mechanical stress to maintain tissue integrity and homeostasis. While mitotic spindles have been shown to reorient in response to external mechanical s...

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Detalles Bibliográficos
Autores principales: Kelkar, Manasi, Bohec, Pierre, Smith, Matthew B., Sreenivasan, Varun, Lisica, Ana, Valon, Léo, Ferber, Emma, Baum, Buzz, Salbreux, Guillaume, Charras, Guillaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245638/
https://www.ncbi.nlm.nih.gov/pubmed/35727980
http://dx.doi.org/10.1073/pnas.2121868119