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Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms
Proper orientation of the mitotic spindle plays a crucial role in embryos, during tissue development, and in adults, where it functions to dissipate mechanical stress to maintain tissue integrity and homeostasis. While mitotic spindles have been shown to reorient in response to external mechanical s...
Autores principales: | Kelkar, Manasi, Bohec, Pierre, Smith, Matthew B., Sreenivasan, Varun, Lisica, Ana, Valon, Léo, Ferber, Emma, Baum, Buzz, Salbreux, Guillaume, Charras, Guillaume |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245638/ https://www.ncbi.nlm.nih.gov/pubmed/35727980 http://dx.doi.org/10.1073/pnas.2121868119 |
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