SARS-CoV-2 couples evasion of inflammatory response to activated nucleotide synthesis

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolves rapidly under the pressure of host immunity, as evidenced by waves of emerging variants despite effective vaccinations, highlighting the need for complementing antivirals. We report that targeting a pyrimidine synthesis enzyme rest...

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Detalles Bibliográficos
Autores principales: Qin, Chao, Rao, Youliang, Yuan, Hao, Wang, Ting-Yu, Zhao, Jun, Espinosa, Bianca, Liu, Yongzhen, Zhang, Shu, Savas, Ali Can, Liu, Qizhi, Zarinfar, Mehrnaz, Rice, Stephanie, Henley, Jill, Comai, Lucio, Graham, Nicholas A., Chen, Casey, Zhang, Chao, Feng, Pinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245715/
https://www.ncbi.nlm.nih.gov/pubmed/35700355
http://dx.doi.org/10.1073/pnas.2122897119

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