Cargando…

The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case

BACKGROUND: Orbital angioleiomyoma is generally considered a rare tumor; approximately 40 cases have been reported. However, after their experience with 6 consecutive cases in their single institution during 3 years, the authors speculate that the incidence of orbital angioleiomyomas is possibly und...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Seonah, Ko, JaeSang, Kim, Se Hoon, Kim, Eui Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245745/
https://www.ncbi.nlm.nih.gov/pubmed/35854868
http://dx.doi.org/10.3171/CASE2172
_version_ 1784738810888716288
author Choi, Seonah
Ko, JaeSang
Kim, Se Hoon
Kim, Eui Hyun
author_facet Choi, Seonah
Ko, JaeSang
Kim, Se Hoon
Kim, Eui Hyun
author_sort Choi, Seonah
collection PubMed
description BACKGROUND: Orbital angioleiomyoma is generally considered a rare tumor; approximately 40 cases have been reported. However, after their experience with 6 consecutive cases in their single institution during 3 years, the authors speculate that the incidence of orbital angioleiomyomas is possibly underestimated. OBSERVATIONS: A 34-year-old female presented with progressive exophthalmos of 2 years’ duration. Orbital computed tomography and magnetic resonance imaging revealed a well-circumscribed orbital tumor with partial and heterogeneous gadolinium enhancement. Technetium-99m red blood cell single-photon emission computed tomography showed positive perfusion in the late blood-pool phase, which was exactly consistent with the finding of a cavernous hemangioma. Under the impression of a cavernous hemangioma, the authors accessed the mass with an endoscopic endonasal approach and completely removed it without neurological deficit. Pathological examination revealed that the final diagnosis was an angioleiomyoma with positive immunostaining results for smooth muscle actin (SMA). LESSONS: The incidence of orbital angioleiomyomas may not be very low, as these lesions have possibly been misdiagnosed as orbital cavernous hemangiomas because of their histological similarity. Preoperative presumption and differentiation from cavernous hemangiomas are very challenging because of the rarity of orbital angioleiomyoma and similar radiological findings. SMA immunostaining may be critical to differentiate orbital angioleiomyomas from cavernous hemangiomas.
format Online
Article
Text
id pubmed-9245745
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher American Association of Neurological Surgeons
record_format MEDLINE/PubMed
spelling pubmed-92457452022-07-18 The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case Choi, Seonah Ko, JaeSang Kim, Se Hoon Kim, Eui Hyun J Neurosurg Case Lessons Case Report BACKGROUND: Orbital angioleiomyoma is generally considered a rare tumor; approximately 40 cases have been reported. However, after their experience with 6 consecutive cases in their single institution during 3 years, the authors speculate that the incidence of orbital angioleiomyomas is possibly underestimated. OBSERVATIONS: A 34-year-old female presented with progressive exophthalmos of 2 years’ duration. Orbital computed tomography and magnetic resonance imaging revealed a well-circumscribed orbital tumor with partial and heterogeneous gadolinium enhancement. Technetium-99m red blood cell single-photon emission computed tomography showed positive perfusion in the late blood-pool phase, which was exactly consistent with the finding of a cavernous hemangioma. Under the impression of a cavernous hemangioma, the authors accessed the mass with an endoscopic endonasal approach and completely removed it without neurological deficit. Pathological examination revealed that the final diagnosis was an angioleiomyoma with positive immunostaining results for smooth muscle actin (SMA). LESSONS: The incidence of orbital angioleiomyomas may not be very low, as these lesions have possibly been misdiagnosed as orbital cavernous hemangiomas because of their histological similarity. Preoperative presumption and differentiation from cavernous hemangiomas are very challenging because of the rarity of orbital angioleiomyoma and similar radiological findings. SMA immunostaining may be critical to differentiate orbital angioleiomyomas from cavernous hemangiomas. American Association of Neurological Surgeons 2021-05-24 /pmc/articles/PMC9245745/ /pubmed/35854868 http://dx.doi.org/10.3171/CASE2172 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Report
Choi, Seonah
Ko, JaeSang
Kim, Se Hoon
Kim, Eui Hyun
The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title_full The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title_fullStr The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title_full_unstemmed The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title_short The underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
title_sort underestimated incidence of an orbital angioleiomyoma is possibly associated with an orbital cavernous hemangioma: illustrative case
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245745/
https://www.ncbi.nlm.nih.gov/pubmed/35854868
http://dx.doi.org/10.3171/CASE2172
work_keys_str_mv AT choiseonah theunderestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kojaesang theunderestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kimsehoon theunderestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kimeuihyun theunderestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT choiseonah underestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kojaesang underestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kimsehoon underestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase
AT kimeuihyun underestimatedincidenceofanorbitalangioleiomyomaispossiblyassociatedwithanorbitalcavernoushemangiomaillustrativecase