Three decades of progress from surgery to medical therapy for isolated neuroaxis BRAF V600E–positive Langerhans cell histiocytosis management: illustrative case

BACKGROUND: “Langerhans cell histiocytosis” (LCH) is a term that encompasses single-system or multisystem disorders traditionally characterized by a proliferation of clonal CD1a+/CD207+ myeloid-derived histiocytes. In most cases of LCH, mitogen-activated protein kinase (MAPK) pathway somatic mutatio...

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Detalles Bibliográficos
Autores principales: Muthiah, Nallammai, Nowicki, Kamil W., Picarsic, Jennifer L., D’Angelo, Michael P., Marker, Daniel F., Andrews, Edward G., Monaco, Edward A., Niranjan, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245772/
https://www.ncbi.nlm.nih.gov/pubmed/35854832
http://dx.doi.org/10.3171/CASE2118

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