Cargando…

Glycoprotein Acetyls: A Novel Inflammatory Biomarker of Early Cardiovascular Risk in the Young

BACKGROUND: Low‐grade inflammation in the young may contribute to the early development of cardiovascular disease. We assessed whether circulating levels of glycoprotein acetyls (GlycA) were better able to predict the development of adverse cardiovascular disease risk profiles compared with the more...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chiesa, Scott T., Charakida, Marietta, Georgiopoulos, Georgios, Roberts, Justin D., Stafford, Simon J., Park, Chloe, Mykkänen, Juha, Kähönen, Mika, Lehtimäki, Terho, Ala‐Korpela, Mika, Raitakari, Olli, Pietiäinen, Milla, Pussinen, Pirkko, Muthurangu, Vivek, Hughes, Alun D., Sattar, Naveed, Timpson, Nicholas J., Deanfield, John E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245818/ https://www.ncbi.nlm.nih.gov/pubmed/35156387 http://dx.doi.org/10.1161/JAHA.121.024380

Ejemplares similares

The effect of apolipoprotein E polymorphism on serum metabolome – a population-based 10-year follow-up study
por: Karjalainen, Juho-Pekka, et al.
Publicado: (2019)

Multi-Omics Integration in a Twin Cohort and Predictive Modeling of Blood Pressure Values
por: Drouard, Gabin, et al.
Publicado: (2022)

Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults
por: Würtz, Peter, et al.
Publicado: (2013)

Cross-sectionally Calculated Metabolic Aging Does Not Relate to Longitudinal Metabolic Changes—Support for Stratified Aging Models
por: Ala-Korpela, Mika, et al.
Publicado: (2023)

Evaluating the direct effects of childhood adiposity on adult systemic metabolism: a multivariable Mendelian randomization analysis
por: Richardson, Tom G, et al.
Publicado: (2021)

Longitudinal metabolomics of increasing body-mass index and waist-hip ratio reveals two dynamic patterns of obesity pandemic
por: Mäkinen, Ville-Petteri, et al.
Publicado: (2023)

Determinants of Intima-Media Thickness in the Young: The ALSPAC Study
por: Chiesa, Scott T., et al.
Publicado: (2021)

Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia
por: Auvinen, Juha, et al.
Publicado: (2021)

NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects
por: Sliz, Eeva, et al.
Publicado: (2018)

Childhood exposure to parental smoking and life-course overweight and central obesity
por: Jaakkola, Johanna M., et al.
Publicado: (2021)

Association between fat mass through adolescence and arterial stiffness: a population-based study from The Avon Longitudinal Study of Parents and Children
por: Dangardt, Frida, et al.
Publicado: (2019)

Genetic and environmental perturbations lead to regulatory decoherence
por: Lea, Amanda, et al.
Publicado: (2019)

Cardiometabolic Health Among Adult Offspring of Hypertensive Pregnancies: The Cardiovascular Risk in Young Finns Study
por: Tapp, Robyn J., et al.
Publicado: (2018)

Assessing the Causal Role of Body Mass Index on Cardiovascular Health in Young Adults: Mendelian Randomization and Recall-by-Genotype Analyses
por: Wade, Kaitlin H., et al.
Publicado: (2018)

Adulthood blood levels of hsa-miR-29b-3p associate with preterm birth and adult metabolic and cognitive health
por: Marttila, Saara, et al.
Publicado: (2021)

Determinants of exercise peak arterial blood pressure, circulatory power, and exercise cardiac power in a population based sample of Finnish male and female aged 30 to 47 years: the Cardiovascular Risk in Young Finns Study
por: Hulkkonen, Janne, et al.
Publicado: (2014)

Reproductive history and blood cell DNA methylation later in life: the Young Finns Study
por: Harville, Emily W., et al.
Publicado: (2021)

Impact of Ideal Cardiovascular Health in Childhood on the Retinal Microvasculature in Midadulthood: Cardiovascular Risk in Young Finns Study
por: Campbell, Matthew D., et al.
Publicado: (2018)

Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis
por: Wang, Qin, et al.
Publicado: (2020)

Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts
por: Ahola-Olli, Ari V., et al.
Publicado: (2019)

A Genome-Wide Association Study Identifies UGT1A1 as a Regulator of Serum Cell-Free DNA in Young Adults: The Cardiovascular Risk in Young Finns Study
por: Jylhävä, Juulia, et al.
Publicado: (2012)

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study
por: Kivimäki, Mika, et al.
Publicado: (2008)

Metabolic profiling of fatty liver in young and middle‐aged adults: Cross‐sectional and prospective analyses of the Young Finns Study
por: Kaikkonen, Jari E., et al.
Publicado: (2016)

EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics
por: Ekholm, Jussi, et al.
Publicado: (2020)

Association of Childhood Oral Infections With Cardiovascular Risk Factors and Subclinical Atherosclerosis in Adulthood
por: Pussinen, Pirkko J., et al.
Publicado: (2019)

Genetic and observational evidence: No independent role for cholesterol efflux over static high‐density lipoprotein concentration measures in coronary heart disease risk assessment
por: Kuusisto, Sanna, et al.
Publicado: (2022)

Common complement factor H polymorphisms are linked with periodontitis in elderly patients
por: Salminen, Aino, et al.
Publicado: (2022)

Blood hsa-miR-122-5p and hsa-miR-885-5p levels associate with fatty liver and related lipoprotein metabolism—The Young Finns Study
por: Raitoharju, Emma, et al.
Publicado: (2016)

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase
por: Würtz, Peter, et al.
Publicado: (2016)

Association of circulating metabolites with healthy diet and risk of cardiovascular disease: analysis of two cohort studies
por: Akbaraly, Tasnime, et al.
Publicado: (2018)

Gene Set Based Integrated Methylome and Transcriptome Analysis Reveals Potential Molecular Mechanisms Linking Cigarette Smoking and Related Diseases
por: Mishra, Pashupati P., et al.
Publicado: (2023)

Assessment of plasma ceramides as predictor for subclinical atherosclerosis
por: Mishra, Pashupati P., et al.
Publicado: (2021)

Exploring Causality between TV Viewing and Weight Change in Young and Middle-Aged Adults. The Cardiovascular Risk in Young Finns Study
por: Helajärvi, Harri, et al.
Publicado: (2014)

Metabolic Signatures of Insulin Resistance in 7,098 Young Adults
por: Würtz, Peter, et al.
Publicado: (2012)

Genetic variation in the hTAS2R38 taste receptor and food consumption among Finnish adults
por: Sandell, Mari, et al.
Publicado: (2014)

A new blood based epigenetic age predictor for adolescents and young adults
por: Aanes, Håvard, et al.
Publicado: (2023)

Circulating Metabolite Predictors of Glycemia in Middle-Aged Men and Women
por: Würtz, Peter, et al.
Publicado: (2012)

Screening for familial hypercholesterolaemia in childhood: Avon Longitudinal Study of Parents and Children (ALSPAC)
por: Futema, Marta, et al.
Publicado: (2017)

Assessing multivariate gene-metabolome associations with rare variants using Bayesian reduced rank regression
por: Marttinen, Pekka, et al.
Publicado: (2014)

Periodontitis and cardiometabolic disorders: The role of lipopolysaccharide and endotoxemia
por: Pussinen, Pirkko J., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_c3btpua5h1pkhdc5c73qo1arr4