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Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case

BACKGROUND: Spinal arachnoid webs are uncommon and difficult to diagnose, especially because causative intradural transverse bands of arachnoid tissue are radiographically occult. Left untreated, arachnoid webs may cause progressive, debilitating, and permanent neurological dysfunction. Conversely,...

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Detalles Bibliográficos
Autores principales: Pham, Nancy, Ebinu, Julius O., Karnati, Tejas, Hacein-Bey, Lotfi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245846/
https://www.ncbi.nlm.nih.gov/pubmed/35855021
http://dx.doi.org/10.3171/CASE2142
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author Pham, Nancy
Ebinu, Julius O.
Karnati, Tejas
Hacein-Bey, Lotfi
author_facet Pham, Nancy
Ebinu, Julius O.
Karnati, Tejas
Hacein-Bey, Lotfi
author_sort Pham, Nancy
collection PubMed
description BACKGROUND: Spinal arachnoid webs are uncommon and difficult to diagnose, especially because causative intradural transverse bands of arachnoid tissue are radiographically occult. Left untreated, arachnoid webs may cause progressive, debilitating, and permanent neurological dysfunction. Conversely, more than 90% of patients may experience rapid neurological recovery after resection, even with a prolonged duration of presenting symptoms. Indirect imaging signs such as spinal cord indentation and compression with cerebrospinal fluid (CSF) flow alteration provide crucial diagnostic clues that are critical in guiding appropriate management of such patients. OBSERVATIONS: The authors reported a patient with no significant medical history who presented with back pain, progressive lower extremity weakness, gait ataxia, and bowel and bladder incontinence. They discussed multimodality imaging for determining the presence of arachnoid webs, including magnetic resonance imaging, phase-contrast CSF flow study, computed tomography myelography, and intraoperative ultrasound. They also discussed the detailed anatomy of the spinal subarachnoid space and a plausible pathophysiological mechanism for dorsal arachnoid webs. LESSONS: The authors report on a patient who underwent comprehensive imaging evaluation detailing the arachnoid web and whose subsequent anatomical localization and surgical treatment resulted in a full neurological recovery.
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spelling pubmed-92458462022-07-18 Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case Pham, Nancy Ebinu, Julius O. Karnati, Tejas Hacein-Bey, Lotfi J Neurosurg Case Lessons Case Lesson BACKGROUND: Spinal arachnoid webs are uncommon and difficult to diagnose, especially because causative intradural transverse bands of arachnoid tissue are radiographically occult. Left untreated, arachnoid webs may cause progressive, debilitating, and permanent neurological dysfunction. Conversely, more than 90% of patients may experience rapid neurological recovery after resection, even with a prolonged duration of presenting symptoms. Indirect imaging signs such as spinal cord indentation and compression with cerebrospinal fluid (CSF) flow alteration provide crucial diagnostic clues that are critical in guiding appropriate management of such patients. OBSERVATIONS: The authors reported a patient with no significant medical history who presented with back pain, progressive lower extremity weakness, gait ataxia, and bowel and bladder incontinence. They discussed multimodality imaging for determining the presence of arachnoid webs, including magnetic resonance imaging, phase-contrast CSF flow study, computed tomography myelography, and intraoperative ultrasound. They also discussed the detailed anatomy of the spinal subarachnoid space and a plausible pathophysiological mechanism for dorsal arachnoid webs. LESSONS: The authors report on a patient who underwent comprehensive imaging evaluation detailing the arachnoid web and whose subsequent anatomical localization and surgical treatment resulted in a full neurological recovery. American Association of Neurological Surgeons 2021-05-17 /pmc/articles/PMC9245846/ /pubmed/35855021 http://dx.doi.org/10.3171/CASE2142 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Lesson
Pham, Nancy
Ebinu, Julius O.
Karnati, Tejas
Hacein-Bey, Lotfi
Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title_full Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title_fullStr Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title_full_unstemmed Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title_short Neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
title_sort neuroimaging findings and pathophysiology of dorsal spinal arachnoid webs: illustrative case
topic Case Lesson
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245846/
https://www.ncbi.nlm.nih.gov/pubmed/35855021
http://dx.doi.org/10.3171/CASE2142
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