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Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-u...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association of Neurological Surgeons
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245851/ https://www.ncbi.nlm.nih.gov/pubmed/35855015 http://dx.doi.org/10.3171/CASE21116 |
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author | Wei, Zhishuo Mallela, Arka N. Faramand, Andrew Niranjan, Ajay Lunsford, L. Dade |
author_facet | Wei, Zhishuo Mallela, Arka N. Faramand, Andrew Niranjan, Ajay Lunsford, L. Dade |
author_sort | Wei, Zhishuo |
collection | PubMed |
description | BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-up of two patients whose recurrent parasagittal meningiomas eventually occluded their superior sagittal sinus. Both patients underwent staged radiosurgery and fractionated radiation therapy to achieve tumor control that extended to 20 years after their initial surgery. After initial subtotal resection of meningiomas that had invaded major cerebral venous sinuses, adjuvant radiosurgery was performed to enhance local tumor control. Over time, adjacent tumor progression required repeat SRS and fractionated radiation therapy to boost long-term tumor response. Staged multimodality intervention led to extended survival in these patients with otherwise unresectable meningiomas. LESSONS: Multimodality management with radiosurgery and fractionated radiation therapy was associated with long-term survival of two patients with otherwise surgically incurable and invasive meningiomas of the dural venous sinuses. |
format | Online Article Text |
id | pubmed-9245851 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Association of Neurological Surgeons |
record_format | MEDLINE/PubMed |
spelling | pubmed-92458512022-07-18 Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases Wei, Zhishuo Mallela, Arka N. Faramand, Andrew Niranjan, Ajay Lunsford, L. Dade J Neurosurg Case Lessons Case Report BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-up of two patients whose recurrent parasagittal meningiomas eventually occluded their superior sagittal sinus. Both patients underwent staged radiosurgery and fractionated radiation therapy to achieve tumor control that extended to 20 years after their initial surgery. After initial subtotal resection of meningiomas that had invaded major cerebral venous sinuses, adjuvant radiosurgery was performed to enhance local tumor control. Over time, adjacent tumor progression required repeat SRS and fractionated radiation therapy to boost long-term tumor response. Staged multimodality intervention led to extended survival in these patients with otherwise unresectable meningiomas. LESSONS: Multimodality management with radiosurgery and fractionated radiation therapy was associated with long-term survival of two patients with otherwise surgically incurable and invasive meningiomas of the dural venous sinuses. American Association of Neurological Surgeons 2021-05-17 /pmc/articles/PMC9245851/ /pubmed/35855015 http://dx.doi.org/10.3171/CASE21116 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ). |
spellingShingle | Case Report Wei, Zhishuo Mallela, Arka N. Faramand, Andrew Niranjan, Ajay Lunsford, L. Dade Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title | Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title_full | Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title_fullStr | Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title_full_unstemmed | Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title_short | Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
title_sort | long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245851/ https://www.ncbi.nlm.nih.gov/pubmed/35855015 http://dx.doi.org/10.3171/CASE21116 |
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