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Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases

BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-u...

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Autores principales: Wei, Zhishuo, Mallela, Arka N., Faramand, Andrew, Niranjan, Ajay, Lunsford, L. Dade
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association of Neurological Surgeons 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245851/
https://www.ncbi.nlm.nih.gov/pubmed/35855015
http://dx.doi.org/10.3171/CASE21116
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author Wei, Zhishuo
Mallela, Arka N.
Faramand, Andrew
Niranjan, Ajay
Lunsford, L. Dade
author_facet Wei, Zhishuo
Mallela, Arka N.
Faramand, Andrew
Niranjan, Ajay
Lunsford, L. Dade
author_sort Wei, Zhishuo
collection PubMed
description BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-up of two patients whose recurrent parasagittal meningiomas eventually occluded their superior sagittal sinus. Both patients underwent staged radiosurgery and fractionated radiation therapy to achieve tumor control that extended to 20 years after their initial surgery. After initial subtotal resection of meningiomas that had invaded major cerebral venous sinuses, adjuvant radiosurgery was performed to enhance local tumor control. Over time, adjacent tumor progression required repeat SRS and fractionated radiation therapy to boost long-term tumor response. Staged multimodality intervention led to extended survival in these patients with otherwise unresectable meningiomas. LESSONS: Multimodality management with radiosurgery and fractionated radiation therapy was associated with long-term survival of two patients with otherwise surgically incurable and invasive meningiomas of the dural venous sinuses.
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spelling pubmed-92458512022-07-18 Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases Wei, Zhishuo Mallela, Arka N. Faramand, Andrew Niranjan, Ajay Lunsford, L. Dade J Neurosurg Case Lessons Case Report BACKGROUND: Invasive sagittal sinus meningiomas are difficult tumors to cure by resection alone. Stereotactic radiosurgery (SRS) can be used as an adjuvant management strategy to improve tumor control after incomplete resection. OBSERVATIONS: The authors reported the long-term retrospective follow-up of two patients whose recurrent parasagittal meningiomas eventually occluded their superior sagittal sinus. Both patients underwent staged radiosurgery and fractionated radiation therapy to achieve tumor control that extended to 20 years after their initial surgery. After initial subtotal resection of meningiomas that had invaded major cerebral venous sinuses, adjuvant radiosurgery was performed to enhance local tumor control. Over time, adjacent tumor progression required repeat SRS and fractionated radiation therapy to boost long-term tumor response. Staged multimodality intervention led to extended survival in these patients with otherwise unresectable meningiomas. LESSONS: Multimodality management with radiosurgery and fractionated radiation therapy was associated with long-term survival of two patients with otherwise surgically incurable and invasive meningiomas of the dural venous sinuses. American Association of Neurological Surgeons 2021-05-17 /pmc/articles/PMC9245851/ /pubmed/35855015 http://dx.doi.org/10.3171/CASE21116 Text en © 2021 The authors https://creativecommons.org/licenses/by-nc-nd/4.0/CC BY-NC-ND 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Case Report
Wei, Zhishuo
Mallela, Arka N.
Faramand, Andrew
Niranjan, Ajay
Lunsford, L. Dade
Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title_full Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title_fullStr Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title_full_unstemmed Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title_short Long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
title_sort long-term survival in patients with long-segment complex meningiomas occluding the dural venous sinuses: illustrative cases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9245851/
https://www.ncbi.nlm.nih.gov/pubmed/35855015
http://dx.doi.org/10.3171/CASE21116
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