Interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms favorably impacts deregulation of oxidative stress genes and antioxidative defense mechanisms

Chronic inflammation is considered a major driving force for clonal expansion and evolution in the Philadelphia-negative myeloproliferative neoplasms, which include essential thrombocythemia, polycythemia vera and primary myelofibrosis (MPNs). One of the key mutation drivers is the JAK2V617F mutatio...

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Detalles Bibliográficos
Autores principales: Skov, Vibe, Thomassen, Mads, Kjær, Lasse, Ellervik, Christina, Larsen, Morten Kranker, Knudsen, Trine Alma, Kruse, Torben A., Hasselbalch, Hans C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246201/
https://www.ncbi.nlm.nih.gov/pubmed/35771847
http://dx.doi.org/10.1371/journal.pone.0270669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246201/
https://www.ncbi.nlm.nih.gov/pubmed/35771847
http://dx.doi.org/10.1371/journal.pone.0270669

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