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Translin facilitates RNA polymerase II dissociation and suppresses genome instability during RNase H2- and Dicer-deficiency
The conserved nucleic acid binding protein Translin contributes to numerous facets of mammalian biology and genetic diseases. It was first identified as a binder of cancer-associated chromosomal translocation breakpoint junctions leading to the suggestion that it was involved in genetic recombinatio...
Autores principales: | Gomez-Escobar, Natalia, Alsaiari, Ahad A. A., Alahamadi, Hanadi A. S., Alzahrani, Othman, Vernon, Ellen, Althagafi, Hussam A. E., Almobadel, Nasser S., Pryce, David W., Wakeman, Jane A., McFarlane, Ramsay J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246224/ https://www.ncbi.nlm.nih.gov/pubmed/35714159 http://dx.doi.org/10.1371/journal.pgen.1010267 |
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