Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review

Papillary renal cell carcinoma (PRCC) is a less common subtype of kidney cancer and is typically more resistant to systemic treatments. This report describes a patient with metastatic type II PRCC who experienced two complete responses (CR) to the tyrosine kinase inhibitor (TKI) sunitinib. The patie...

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Autores principales: Al Ashour, Bayan H, Azam, Faisal, Ibnshamsah, Fahad, Alrowais, Fahad, Al-Garni, Ayed, Al-Shamsi, Humaid O, Bukhari, Nedal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246320/
https://www.ncbi.nlm.nih.gov/pubmed/35800817
http://dx.doi.org/10.7759/cureus.25541
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author Al Ashour, Bayan H
Azam, Faisal
Ibnshamsah, Fahad
Alrowais, Fahad
Al-Garni, Ayed
Al-Shamsi, Humaid O
Bukhari, Nedal
author_facet Al Ashour, Bayan H
Azam, Faisal
Ibnshamsah, Fahad
Alrowais, Fahad
Al-Garni, Ayed
Al-Shamsi, Humaid O
Bukhari, Nedal
author_sort Al Ashour, Bayan H
collection PubMed
description Papillary renal cell carcinoma (PRCC) is a less common subtype of kidney cancer and is typically more resistant to systemic treatments. This report describes a patient with metastatic type II PRCC who experienced two complete responses (CR) to the tyrosine kinase inhibitor (TKI) sunitinib. The patient remains on sunitinib with durable control of the disease. To the best of our knowledge, this is the first case of metastatic type II PRCC with CR to sunitinib.
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spelling pubmed-92463202022-07-06 Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review Al Ashour, Bayan H Azam, Faisal Ibnshamsah, Fahad Alrowais, Fahad Al-Garni, Ayed Al-Shamsi, Humaid O Bukhari, Nedal Cureus Internal Medicine Papillary renal cell carcinoma (PRCC) is a less common subtype of kidney cancer and is typically more resistant to systemic treatments. This report describes a patient with metastatic type II PRCC who experienced two complete responses (CR) to the tyrosine kinase inhibitor (TKI) sunitinib. The patient remains on sunitinib with durable control of the disease. To the best of our knowledge, this is the first case of metastatic type II PRCC with CR to sunitinib. Cureus 2022-05-31 /pmc/articles/PMC9246320/ /pubmed/35800817 http://dx.doi.org/10.7759/cureus.25541 Text en Copyright © 2022, Al Ashour et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Al Ashour, Bayan H
Azam, Faisal
Ibnshamsah, Fahad
Alrowais, Fahad
Al-Garni, Ayed
Al-Shamsi, Humaid O
Bukhari, Nedal
Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title_full Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title_fullStr Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title_full_unstemmed Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title_short Metastatic Type II Papillary Renal Cell Carcinoma With Recurrent Complete Responses to Sunitinib: A Case Report With a Literature Review
title_sort metastatic type ii papillary renal cell carcinoma with recurrent complete responses to sunitinib: a case report with a literature review
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246320/
https://www.ncbi.nlm.nih.gov/pubmed/35800817
http://dx.doi.org/10.7759/cureus.25541
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