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A native chemical chaperone in the human eye lens

Cataract is one of the most prevalent protein aggregation disorders and still the most common cause of vision loss worldwide. The metabolically quiescent core region of the human lens lacks cellular or protein turnover; it has therefore evolved remarkable mechanisms to resist light-scattering protei...

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Detalles Bibliográficos
Autores principales:	Serebryany, Eugene, Chowdhury, Sourav, Woods, Christopher N, Thorn, David C, Watson, Nicki E, McClelland, Arthur A, Klevit, Rachel E, Shakhnovich, Eugene I
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246369/ https://www.ncbi.nlm.nih.gov/pubmed/35723573 http://dx.doi.org/10.7554/eLife.76923

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