Breast cancer chemotherapy induces vascular dysfunction and hypertension through a NOX4-dependent mechanism

Cardiovascular disease is the major cause of morbidity and mortality in breast cancer survivors. Chemotherapy contributes to this risk. We aimed to define the mechanisms of long-term vascular dysfunction caused by neoadjuvant chemotherapy (NACT) and identify novel therapeutic targets. We studied art...

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Detalles Bibliográficos
Autores principales: Szczepaniak, Piotr, Siedlinski, Mateusz, Hodorowicz-Zaniewska, Diana, Nosalski, Ryszard, Mikolajczyk, Tomasz P., Dobosz, Aneta M., Dikalova, Anna, Dikalov, Sergey, Streb, Joanna, Gara, Katarzyna, Basta, Pawel, Krolczyk, Jaroslaw, Sulicka-Grodzicka, Joanna, Jozefczuk, Ewelina, Dziewulska, Anna, Saju, Blessy, Laksa, Iwona, Chen, Wei, Dormer, John, Tomaszewski, Maciej, Maffia, Pasquale, Czesnikiewicz-Guzik, Marta, Crea, Filippo, Dobrzyn, Agnieszka, Moslehi, Javid, Grodzicki, Tomasz, Harrison, David G., Guzik, Tomasz J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246378/
https://www.ncbi.nlm.nih.gov/pubmed/35617030
http://dx.doi.org/10.1172/JCI149117

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