Stromal Notch ligands foster lymphopenia-driven functional plasticity and homeostatic proliferation of naive B cells

In lymphopenic environments, secondary lymphoid organs regulate the size of B and T cell compartments by supporting the homeostatic proliferation of mature lymphocytes. The molecular mechanisms underlying these responses and their functional consequences remain incompletely understood. To evaluate h...

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Detalles Bibliográficos
Autores principales: Gómez Atria, Daniela, Gaudette, Brian T., Londregan, Jennifer, Kelly, Samantha, Perkey, Eric, Allman, Anneka, Srivastava, Bhaskar, Koch, Ute, Radtke, Freddy, Ludewig, Burkhard, Siebel, Christian W., Ryan, Russell J.H., Robertson, Tanner F., Burkhardt, Janis K., Pear, Warren S., Allman, David, Maillard, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246379/
https://www.ncbi.nlm.nih.gov/pubmed/35579963
http://dx.doi.org/10.1172/JCI158885

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