Bitter taste signaling in tracheal epithelial brush cells elicits innate immune responses to bacterial infection

Constant exposure of the airways to inhaled pathogens requires efficient early immune responses protecting against infections. How bacteria on the epithelial surface are detected and first-line protective mechanisms are initiated are not well understood. We have recently shown that tracheal brush ce...

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Detalles Bibliográficos
Autores principales: Hollenhorst, Monika I., Nandigama, Rajender, Evers, Saskia B., Gamayun, Igor, Abdel Wadood, Noran, Salah, Alaa, Pieper, Mario, Wyatt, Amanda, Stukalov, Alexey, Gebhardt, Anna, Nadolni, Wiebke, Burow, Wera, Herr, Christian, Beisswenger, Christoph, Kusumakshi, Soumya, Ectors, Fabien, Kichko, Tatjana I., Hübner, Lisa, Reeh, Peter, Munder, Antje, Wienhold, Sandra-Maria, Witzenrath, Martin, Bals, Robert, Flockerzi, Veit, Gudermann, Thomas, Bischoff, Markus, Lipp, Peter, Zierler, Susanna, Chubanov, Vladimir, Pichlmair, Andreas, König, Peter, Boehm, Ulrich, Krasteva-Christ, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246383/
https://www.ncbi.nlm.nih.gov/pubmed/35503420
http://dx.doi.org/10.1172/JCI150951

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