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miR-181b targets semaphorin 3A to mediate TGF-β–induced endothelial-mesenchymal transition related to atrial fibrillation

Atrial fibrosis is an essential contributor to atrial fibrillation (AF). It remains unclear whether atrial endocardial endothelial cells (AEECs) that undergo endothelial-mesenchymal transition (EndMT) are among the sources of atrial fibroblasts. We studied human atria, TGF-β–treated human AEECs, car...

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Detalles Bibliográficos
Autores principales: Lai, Ying-Ju, Tsai, Feng-Chun, Chang, Gwo-Jyh, Chang, Shang-Hung, Huang, Chung-Chi, Chen, Wei-Jan, Yeh, Yung-Hsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246393/
https://www.ncbi.nlm.nih.gov/pubmed/35775491
http://dx.doi.org/10.1172/JCI142548

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