Specific in situ inflammatory states associate with progression to renal failure in lupus nephritis

BACKGROUND: In human lupus nephritis (LN), tubulointerstitial inflammation (TII) on biopsy predicts progression to end-stage renal disease (ESRD). However, only about half of patients with moderate-to-severe TII develop ESRD. We hypothesized that this heterogeneity in outcome reflects different unde...

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Detalles Bibliográficos
Autores principales: Abraham, Rebecca, Durkee, Madeleine S., Ai, Junting, Veselits, Margaret, Casella, Gabriel, Asano, Yuta, Chang, Anthony, Ko, Kichul, Oshinsky, Charles, Peninger, Emily, Giger, Maryellen L., Clark, Marcus R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246394/
https://www.ncbi.nlm.nih.gov/pubmed/35608910
http://dx.doi.org/10.1172/JCI155350

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