Cargando…

Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports

INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging cha...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Chenliang, Wang, Yiyun, Chen, Zonghui, Qian, Guowei, Yu, Wenxi, Wang, Yong, Zheng, Shuier, Shen, Zan, Li, Hongtao, Wang, Yonggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246414/
https://www.ncbi.nlm.nih.gov/pubmed/35785166
http://dx.doi.org/10.3389/fonc.2022.926387
_version_ 1784738965518024704
author Zhou, Chenliang
Wang, Yiyun
Chen, Zonghui
Qian, Guowei
Yu, Wenxi
Wang, Yong
Zheng, Shuier
Shen, Zan
Li, Hongtao
Wang, Yonggang
author_facet Zhou, Chenliang
Wang, Yiyun
Chen, Zonghui
Qian, Guowei
Yu, Wenxi
Wang, Yong
Zheng, Shuier
Shen, Zan
Li, Hongtao
Wang, Yonggang
author_sort Zhou, Chenliang
collection PubMed
description INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging characteristics. METHODS: The features, treatments, and outcomes of 5 bone sarcoma pediatric patients with PORTs who suffered from cardiac masses in the right atrium were analyzed. Clinical data and histological characteristics of cardiac masses were also recorded. RESULTS: Among 928 patients with malignancy and PORTs, 5 bone sarcoma pediatric patients were found to have cardiac masses in the right atrium. The catheter tips were located in the right atrium of 4 patients and the superior vena cava-right atrium junction (CAJ) of 1 patient. Four patients with good response to anti-tumor treatment had received surgical lumpectomies for pathologic identification and mass excision, with cardiac metastases among 1 patient and thromboses among 3 patients. The median time from venous access port implantation to cardiac mass detection for CRAT was 6.3 months (range: 4.7–6.8 months) and to diagnosis of or possible cardiac metastasis was 13.3 months (range: 11.2–15.4 months). CONCLUSION: The placement of a catheter tip into the right atrium should be avoided. The time from PORTs implantation to cardiac mass detection might serve as a potential tool to differentiate cardiac metastasis from CRAT. Surgical management may be an effective treatment for bone sarcoma pediatric patients who had good response to anti-tumor treatment and suffered from cardiac masses in the right atrium.
format Online
Article
Text
id pubmed-9246414
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-92464142022-07-01 Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports Zhou, Chenliang Wang, Yiyun Chen, Zonghui Qian, Guowei Yu, Wenxi Wang, Yong Zheng, Shuier Shen, Zan Li, Hongtao Wang, Yonggang Front Oncol Oncology INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging characteristics. METHODS: The features, treatments, and outcomes of 5 bone sarcoma pediatric patients with PORTs who suffered from cardiac masses in the right atrium were analyzed. Clinical data and histological characteristics of cardiac masses were also recorded. RESULTS: Among 928 patients with malignancy and PORTs, 5 bone sarcoma pediatric patients were found to have cardiac masses in the right atrium. The catheter tips were located in the right atrium of 4 patients and the superior vena cava-right atrium junction (CAJ) of 1 patient. Four patients with good response to anti-tumor treatment had received surgical lumpectomies for pathologic identification and mass excision, with cardiac metastases among 1 patient and thromboses among 3 patients. The median time from venous access port implantation to cardiac mass detection for CRAT was 6.3 months (range: 4.7–6.8 months) and to diagnosis of or possible cardiac metastasis was 13.3 months (range: 11.2–15.4 months). CONCLUSION: The placement of a catheter tip into the right atrium should be avoided. The time from PORTs implantation to cardiac mass detection might serve as a potential tool to differentiate cardiac metastasis from CRAT. Surgical management may be an effective treatment for bone sarcoma pediatric patients who had good response to anti-tumor treatment and suffered from cardiac masses in the right atrium. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9246414/ /pubmed/35785166 http://dx.doi.org/10.3389/fonc.2022.926387 Text en Copyright © 2022 Zhou, Wang, Chen, Qian, Yu, Wang, Zheng, Shen, Li and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Zhou, Chenliang
Wang, Yiyun
Chen, Zonghui
Qian, Guowei
Yu, Wenxi
Wang, Yong
Zheng, Shuier
Shen, Zan
Li, Hongtao
Wang, Yonggang
Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title_full Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title_fullStr Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title_full_unstemmed Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title_short Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
title_sort surgical management of cardiac masses in right atrium among bone sarcoma pediatric patients with totally implanted ports
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246414/
https://www.ncbi.nlm.nih.gov/pubmed/35785166
http://dx.doi.org/10.3389/fonc.2022.926387
work_keys_str_mv AT zhouchenliang surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT wangyiyun surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT chenzonghui surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT qianguowei surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT yuwenxi surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT wangyong surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT zhengshuier surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT shenzan surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT lihongtao surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports
AT wangyonggang surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports