Cargando…
Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports
INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging cha...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246414/ https://www.ncbi.nlm.nih.gov/pubmed/35785166 http://dx.doi.org/10.3389/fonc.2022.926387 |
_version_ | 1784738965518024704 |
---|---|
author | Zhou, Chenliang Wang, Yiyun Chen, Zonghui Qian, Guowei Yu, Wenxi Wang, Yong Zheng, Shuier Shen, Zan Li, Hongtao Wang, Yonggang |
author_facet | Zhou, Chenliang Wang, Yiyun Chen, Zonghui Qian, Guowei Yu, Wenxi Wang, Yong Zheng, Shuier Shen, Zan Li, Hongtao Wang, Yonggang |
author_sort | Zhou, Chenliang |
collection | PubMed |
description | INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging characteristics. METHODS: The features, treatments, and outcomes of 5 bone sarcoma pediatric patients with PORTs who suffered from cardiac masses in the right atrium were analyzed. Clinical data and histological characteristics of cardiac masses were also recorded. RESULTS: Among 928 patients with malignancy and PORTs, 5 bone sarcoma pediatric patients were found to have cardiac masses in the right atrium. The catheter tips were located in the right atrium of 4 patients and the superior vena cava-right atrium junction (CAJ) of 1 patient. Four patients with good response to anti-tumor treatment had received surgical lumpectomies for pathologic identification and mass excision, with cardiac metastases among 1 patient and thromboses among 3 patients. The median time from venous access port implantation to cardiac mass detection for CRAT was 6.3 months (range: 4.7–6.8 months) and to diagnosis of or possible cardiac metastasis was 13.3 months (range: 11.2–15.4 months). CONCLUSION: The placement of a catheter tip into the right atrium should be avoided. The time from PORTs implantation to cardiac mass detection might serve as a potential tool to differentiate cardiac metastasis from CRAT. Surgical management may be an effective treatment for bone sarcoma pediatric patients who had good response to anti-tumor treatment and suffered from cardiac masses in the right atrium. |
format | Online Article Text |
id | pubmed-9246414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92464142022-07-01 Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports Zhou, Chenliang Wang, Yiyun Chen, Zonghui Qian, Guowei Yu, Wenxi Wang, Yong Zheng, Shuier Shen, Zan Li, Hongtao Wang, Yonggang Front Oncol Oncology INTRODUCTION: Totally implanted ports (PORTs) have been widely used among patients with malignancy. Cardiac metastasis secondary to bone sarcoma and catheter-related right atrial thrombosis (CRAT) can be both present as cardiac masses. However, these two cardiac masses share very similar imaging characteristics. METHODS: The features, treatments, and outcomes of 5 bone sarcoma pediatric patients with PORTs who suffered from cardiac masses in the right atrium were analyzed. Clinical data and histological characteristics of cardiac masses were also recorded. RESULTS: Among 928 patients with malignancy and PORTs, 5 bone sarcoma pediatric patients were found to have cardiac masses in the right atrium. The catheter tips were located in the right atrium of 4 patients and the superior vena cava-right atrium junction (CAJ) of 1 patient. Four patients with good response to anti-tumor treatment had received surgical lumpectomies for pathologic identification and mass excision, with cardiac metastases among 1 patient and thromboses among 3 patients. The median time from venous access port implantation to cardiac mass detection for CRAT was 6.3 months (range: 4.7–6.8 months) and to diagnosis of or possible cardiac metastasis was 13.3 months (range: 11.2–15.4 months). CONCLUSION: The placement of a catheter tip into the right atrium should be avoided. The time from PORTs implantation to cardiac mass detection might serve as a potential tool to differentiate cardiac metastasis from CRAT. Surgical management may be an effective treatment for bone sarcoma pediatric patients who had good response to anti-tumor treatment and suffered from cardiac masses in the right atrium. Frontiers Media S.A. 2022-06-16 /pmc/articles/PMC9246414/ /pubmed/35785166 http://dx.doi.org/10.3389/fonc.2022.926387 Text en Copyright © 2022 Zhou, Wang, Chen, Qian, Yu, Wang, Zheng, Shen, Li and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Zhou, Chenliang Wang, Yiyun Chen, Zonghui Qian, Guowei Yu, Wenxi Wang, Yong Zheng, Shuier Shen, Zan Li, Hongtao Wang, Yonggang Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title | Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title_full | Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title_fullStr | Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title_full_unstemmed | Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title_short | Surgical Management of Cardiac Masses in Right Atrium Among Bone Sarcoma Pediatric Patients With Totally Implanted Ports |
title_sort | surgical management of cardiac masses in right atrium among bone sarcoma pediatric patients with totally implanted ports |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246414/ https://www.ncbi.nlm.nih.gov/pubmed/35785166 http://dx.doi.org/10.3389/fonc.2022.926387 |
work_keys_str_mv | AT zhouchenliang surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT wangyiyun surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT chenzonghui surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT qianguowei surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT yuwenxi surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT wangyong surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT zhengshuier surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT shenzan surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT lihongtao surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports AT wangyonggang surgicalmanagementofcardiacmassesinrightatriumamongbonesarcomapediatricpatientswithtotallyimplantedports |