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An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer

In this review, we aim to update readers about the most recent studies on common pharmaceuticals and their association with pancreatic cancer risk. The use of prophylactic aspirin, metformin, beta-blockers, and statins has been studied in the past but showed inconclusive results in the reduction of...

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Detalles Bibliográficos
Autores principales: Miyaki, Candace, Lynch, Launa M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246430/
https://www.ncbi.nlm.nih.gov/pubmed/35800820
http://dx.doi.org/10.7759/cureus.25496
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author Miyaki, Candace
Lynch, Launa M
author_facet Miyaki, Candace
Lynch, Launa M
author_sort Miyaki, Candace
collection PubMed
description In this review, we aim to update readers about the most recent studies on common pharmaceuticals and their association with pancreatic cancer risk. The use of prophylactic aspirin, metformin, beta-blockers, and statins has been studied in the past but showed inconclusive results in the reduction of pancreatic cancer incidence. However, in recent studies, these medications along with combination therapy of aspirin and metformin were found to have a more significant association with decreasing risk. Given the poor prognosis of pancreatic cancer despite treatment, medication prophylaxis prevention should be considered. In this review, we hope to encourage future case-control or prospective studies on common medications that have shown great potential in delaying pancreatic cancer development.
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spelling pubmed-92464302022-07-06 An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer Miyaki, Candace Lynch, Launa M Cureus Endocrinology/Diabetes/Metabolism In this review, we aim to update readers about the most recent studies on common pharmaceuticals and their association with pancreatic cancer risk. The use of prophylactic aspirin, metformin, beta-blockers, and statins has been studied in the past but showed inconclusive results in the reduction of pancreatic cancer incidence. However, in recent studies, these medications along with combination therapy of aspirin and metformin were found to have a more significant association with decreasing risk. Given the poor prognosis of pancreatic cancer despite treatment, medication prophylaxis prevention should be considered. In this review, we hope to encourage future case-control or prospective studies on common medications that have shown great potential in delaying pancreatic cancer development. Cureus 2022-05-30 /pmc/articles/PMC9246430/ /pubmed/35800820 http://dx.doi.org/10.7759/cureus.25496 Text en Copyright © 2022, Miyaki et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Endocrinology/Diabetes/Metabolism
Miyaki, Candace
Lynch, Launa M
An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title_full An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title_fullStr An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title_full_unstemmed An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title_short An Update on Common Pharmaceuticals in the Prevention of Pancreatic Cancer
title_sort update on common pharmaceuticals in the prevention of pancreatic cancer
topic Endocrinology/Diabetes/Metabolism
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246430/
https://www.ncbi.nlm.nih.gov/pubmed/35800820
http://dx.doi.org/10.7759/cureus.25496
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