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Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study

Background: Even with the wide base of knowledge that has been accumulated regarding coronavirus disease 2019 (COVID-19), only limited studies have tried to establish differences in outcomes of elderly patients hospitalized with COVID-19. We, thus, conducted a retrospective study on a large cohort o...

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Autores principales: Mittal, Kartik, Dhar, Minakshi, Pathania, Monika, Saxena, Vartika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246440/
https://www.ncbi.nlm.nih.gov/pubmed/35800824
http://dx.doi.org/10.7759/cureus.25506
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author Mittal, Kartik
Dhar, Minakshi
Pathania, Monika
Saxena, Vartika
author_facet Mittal, Kartik
Dhar, Minakshi
Pathania, Monika
Saxena, Vartika
author_sort Mittal, Kartik
collection PubMed
description Background: Even with the wide base of knowledge that has been accumulated regarding coronavirus disease 2019 (COVID-19), only limited studies have tried to establish differences in outcomes of elderly patients hospitalized with COVID-19. We, thus, conducted a retrospective study on a large cohort of hospitalized patients with COVID-19 to improve the understanding of such differences and add to the evidence available regarding this age group.  Methods: This is a single-centre retrospective study conducted at a tertiary level hospital in the state of Uttarakhand in North India to determine clinical characteristics and outcomes in elderly patients (≥ 60 years) hospitalized with COVID-19 between May 1, 2020, and May 31, 2021. Our study included a retrospective follow-up at six months to also determine rehospitalizations and post-discharge mortality. Results: There was a statistically significant difference (p<0.05) in in-hospital mortality, various in-hospital complications, duration of stay, number of rehospitalizations at six months, and post-discharge mortality up to six months in the elderly age group hospitalized with COVID-19. Conclusions: This retrospective study demonstrates that the clinical characteristics and outcomes in hospitalized elderly with COVID-19 differ significantly from the younger adult population and demonstrates a need for greater hospital resource utilization in this age group. These results will help policymakers be better prepared for future pandemics. 
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spelling pubmed-92464402022-07-06 Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study Mittal, Kartik Dhar, Minakshi Pathania, Monika Saxena, Vartika Cureus Internal Medicine Background: Even with the wide base of knowledge that has been accumulated regarding coronavirus disease 2019 (COVID-19), only limited studies have tried to establish differences in outcomes of elderly patients hospitalized with COVID-19. We, thus, conducted a retrospective study on a large cohort of hospitalized patients with COVID-19 to improve the understanding of such differences and add to the evidence available regarding this age group.  Methods: This is a single-centre retrospective study conducted at a tertiary level hospital in the state of Uttarakhand in North India to determine clinical characteristics and outcomes in elderly patients (≥ 60 years) hospitalized with COVID-19 between May 1, 2020, and May 31, 2021. Our study included a retrospective follow-up at six months to also determine rehospitalizations and post-discharge mortality. Results: There was a statistically significant difference (p<0.05) in in-hospital mortality, various in-hospital complications, duration of stay, number of rehospitalizations at six months, and post-discharge mortality up to six months in the elderly age group hospitalized with COVID-19. Conclusions: This retrospective study demonstrates that the clinical characteristics and outcomes in hospitalized elderly with COVID-19 differ significantly from the younger adult population and demonstrates a need for greater hospital resource utilization in this age group. These results will help policymakers be better prepared for future pandemics.  Cureus 2022-05-30 /pmc/articles/PMC9246440/ /pubmed/35800824 http://dx.doi.org/10.7759/cureus.25506 Text en Copyright © 2022, Mittal et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Mittal, Kartik
Dhar, Minakshi
Pathania, Monika
Saxena, Vartika
Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title_full Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title_fullStr Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title_full_unstemmed Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title_short Clinical Characteristics and Outcomes in Elderly Patients With COVID-19: A Single-Centre Retrospective Study
title_sort clinical characteristics and outcomes in elderly patients with covid-19: a single-centre retrospective study
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246440/
https://www.ncbi.nlm.nih.gov/pubmed/35800824
http://dx.doi.org/10.7759/cureus.25506
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