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Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae

Freshwater-related infections can be caused by a broad range of pathogens, potentially leading to skin and soft tissue, pulmonary, gastrointestinal, or even systemic diseases. Haematospirillum jordaniae (H. jordaniae),a gram-negative, aerobic organism previously regarded solely as an environmental m...

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Autores principales: Creech, Zachary A, Truong, Gia Thinh D, Kenny, Dorothy X, Butt, Dua Noor, Li, Changzhao, Cavalieri, Stephen, El-Herte, Rima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246461/
https://www.ncbi.nlm.nih.gov/pubmed/35800845
http://dx.doi.org/10.7759/cureus.25480
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author Creech, Zachary A
Truong, Gia Thinh D
Kenny, Dorothy X
Butt, Dua Noor
Li, Changzhao
Cavalieri, Stephen
El-Herte, Rima
author_facet Creech, Zachary A
Truong, Gia Thinh D
Kenny, Dorothy X
Butt, Dua Noor
Li, Changzhao
Cavalieri, Stephen
El-Herte, Rima
author_sort Creech, Zachary A
collection PubMed
description Freshwater-related infections can be caused by a broad range of pathogens, potentially leading to skin and soft tissue, pulmonary, gastrointestinal, or even systemic diseases. Haematospirillum jordaniae (H. jordaniae),a gram-negative, aerobic organism previously regarded solely as an environmental microbe, has been classified as a pathogen capable of causing human infection in the United States. There has been only one other case reported in the literature of H. jordaniae infection, and little is known about the pathogenesis.The presentation and progression of clinical symptoms in our cases indicate freshwater cutaneous injury as the most likely route of H. jordaniae infection. We present two cases of H. jordaniae infection in elderly males. Both patients had freshwater exposure and skin injury resulting in sepsis, cellulitis at the site of injury, and bacteremia. Additionally, one patient presented with an acute deep venous thrombosis. The diagnosis of H. jordaniae was confirmed using Sanger sequencing 16s ribosomal RNA data. Antimicrobial therapy included piperacillin-tazobactam, ceftazidime, and levofloxacin. Both patients recovered successfully. While clinical cases and literature involving the newly classified human pathogen H. jordaniae are still rare, it is crucial to recognize the potential emergence of environmental organisms, previously believed to be harmless, as human pathogens. In cases of bacteremia and cellulitis with recent freshwater exposure and injury, H. jordaniae infection should be considered as part of the differential diagnosis.
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spelling pubmed-92464612022-07-06 Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae Creech, Zachary A Truong, Gia Thinh D Kenny, Dorothy X Butt, Dua Noor Li, Changzhao Cavalieri, Stephen El-Herte, Rima Cureus Internal Medicine Freshwater-related infections can be caused by a broad range of pathogens, potentially leading to skin and soft tissue, pulmonary, gastrointestinal, or even systemic diseases. Haematospirillum jordaniae (H. jordaniae),a gram-negative, aerobic organism previously regarded solely as an environmental microbe, has been classified as a pathogen capable of causing human infection in the United States. There has been only one other case reported in the literature of H. jordaniae infection, and little is known about the pathogenesis.The presentation and progression of clinical symptoms in our cases indicate freshwater cutaneous injury as the most likely route of H. jordaniae infection. We present two cases of H. jordaniae infection in elderly males. Both patients had freshwater exposure and skin injury resulting in sepsis, cellulitis at the site of injury, and bacteremia. Additionally, one patient presented with an acute deep venous thrombosis. The diagnosis of H. jordaniae was confirmed using Sanger sequencing 16s ribosomal RNA data. Antimicrobial therapy included piperacillin-tazobactam, ceftazidime, and levofloxacin. Both patients recovered successfully. While clinical cases and literature involving the newly classified human pathogen H. jordaniae are still rare, it is crucial to recognize the potential emergence of environmental organisms, previously believed to be harmless, as human pathogens. In cases of bacteremia and cellulitis with recent freshwater exposure and injury, H. jordaniae infection should be considered as part of the differential diagnosis. Cureus 2022-05-30 /pmc/articles/PMC9246461/ /pubmed/35800845 http://dx.doi.org/10.7759/cureus.25480 Text en Copyright © 2022, Creech et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Creech, Zachary A
Truong, Gia Thinh D
Kenny, Dorothy X
Butt, Dua Noor
Li, Changzhao
Cavalieri, Stephen
El-Herte, Rima
Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title_full Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title_fullStr Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title_full_unstemmed Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title_short Unusual Freshwater-Related Infections Caused by Haematospirillum jordaniae
title_sort unusual freshwater-related infections caused by haematospirillum jordaniae
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246461/
https://www.ncbi.nlm.nih.gov/pubmed/35800845
http://dx.doi.org/10.7759/cureus.25480
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