Cargando…

Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India

Introduction: Preterm premature rupture of membranes (PPROM) is the spontaneous rupture of the fetal membranes before the completion of 37 weeks of pregnancy. PPROM occurs in 3% of pregnancies. Methodology: This prospective observational study was conducted between September 2019 and March 2021, inv...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, Neha, Pattnaik, Lipipuspa, Panda, Soumya R, Jena, Pramila, Panda, Jyochnamayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246467/
https://www.ncbi.nlm.nih.gov/pubmed/35800788
http://dx.doi.org/10.7759/cureus.25533
_version_ 1784738978884222976
author Singh, Neha
Pattnaik, Lipipuspa
Panda, Soumya R
Jena, Pramila
Panda, Jyochnamayi
author_facet Singh, Neha
Pattnaik, Lipipuspa
Panda, Soumya R
Jena, Pramila
Panda, Jyochnamayi
author_sort Singh, Neha
collection PubMed
description Introduction: Preterm premature rupture of membranes (PPROM) is the spontaneous rupture of the fetal membranes before the completion of 37 weeks of pregnancy. PPROM occurs in 3% of pregnancies. Methodology: This prospective observational study was conducted between September 2019 and March 2021, involving 150 antenatal patients attending our outpatient department or labor room. All pregnant women with a singleton pregnancy between 28 and 37 weeks of gestational age with PPROM were included in our study. Results: A total of 44% of women were admitted to the hospital within 6-11 hours of the onset of PPROM, while 34% of women were admitted within five hours and 15.33% were admitted within 12-23 hours of the onset of PPROM. The most common organisms isolated in high vaginal swabs were Enterococcus faecalis (18%), Escherichia coli (12%), Staphylococcus aureus (12.66%), Staphylococcus haemolyticus (6.66%), and Candida albicans (4.66%). Around 74.66% of women were delivered within 24 hours of the onset of PPROM, whereas only 2.6% of patients were delivered after 72 hours and the rest 34% were delivered between 25 and 72 hours. Of our study subjects, 10% were febrile, 4% were having urinary tract infections, 2.5% had postpartum hemorrhage, and 2% had chorioamnionitis. As far as neonatal morbidity and mortality are concerned, birth asphyxia and jaundice were seen in 12% of patients each, whereas septicemia was found in 4% of study subjects. Conclusion: Owing to the association of higher maternal and perinatal morbidity and mortality, cases, especially in the early PPROM group, should be strictly monitored for clinical and laboratory signs of chorioamnionitis while opting for conservative management.
format Online
Article
Text
id pubmed-9246467
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-92464672022-07-06 Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India Singh, Neha Pattnaik, Lipipuspa Panda, Soumya R Jena, Pramila Panda, Jyochnamayi Cureus Obstetrics/Gynecology Introduction: Preterm premature rupture of membranes (PPROM) is the spontaneous rupture of the fetal membranes before the completion of 37 weeks of pregnancy. PPROM occurs in 3% of pregnancies. Methodology: This prospective observational study was conducted between September 2019 and March 2021, involving 150 antenatal patients attending our outpatient department or labor room. All pregnant women with a singleton pregnancy between 28 and 37 weeks of gestational age with PPROM were included in our study. Results: A total of 44% of women were admitted to the hospital within 6-11 hours of the onset of PPROM, while 34% of women were admitted within five hours and 15.33% were admitted within 12-23 hours of the onset of PPROM. The most common organisms isolated in high vaginal swabs were Enterococcus faecalis (18%), Escherichia coli (12%), Staphylococcus aureus (12.66%), Staphylococcus haemolyticus (6.66%), and Candida albicans (4.66%). Around 74.66% of women were delivered within 24 hours of the onset of PPROM, whereas only 2.6% of patients were delivered after 72 hours and the rest 34% were delivered between 25 and 72 hours. Of our study subjects, 10% were febrile, 4% were having urinary tract infections, 2.5% had postpartum hemorrhage, and 2% had chorioamnionitis. As far as neonatal morbidity and mortality are concerned, birth asphyxia and jaundice were seen in 12% of patients each, whereas septicemia was found in 4% of study subjects. Conclusion: Owing to the association of higher maternal and perinatal morbidity and mortality, cases, especially in the early PPROM group, should be strictly monitored for clinical and laboratory signs of chorioamnionitis while opting for conservative management. Cureus 2022-05-31 /pmc/articles/PMC9246467/ /pubmed/35800788 http://dx.doi.org/10.7759/cureus.25533 Text en Copyright © 2022, Singh et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Singh, Neha
Pattnaik, Lipipuspa
Panda, Soumya R
Jena, Pramila
Panda, Jyochnamayi
Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title_full Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title_fullStr Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title_full_unstemmed Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title_short Fetomaternal Outcomes in Women Affected With Preterm Premature Rupture of Membranes: An Observational Study From a Tertiary Care Center in Eastern India
title_sort fetomaternal outcomes in women affected with preterm premature rupture of membranes: an observational study from a tertiary care center in eastern india
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246467/
https://www.ncbi.nlm.nih.gov/pubmed/35800788
http://dx.doi.org/10.7759/cureus.25533
work_keys_str_mv AT singhneha fetomaternaloutcomesinwomenaffectedwithpretermprematureruptureofmembranesanobservationalstudyfromatertiarycarecenterineasternindia
AT pattnaiklipipuspa fetomaternaloutcomesinwomenaffectedwithpretermprematureruptureofmembranesanobservationalstudyfromatertiarycarecenterineasternindia
AT pandasoumyar fetomaternaloutcomesinwomenaffectedwithpretermprematureruptureofmembranesanobservationalstudyfromatertiarycarecenterineasternindia
AT jenapramila fetomaternaloutcomesinwomenaffectedwithpretermprematureruptureofmembranesanobservationalstudyfromatertiarycarecenterineasternindia
AT pandajyochnamayi fetomaternaloutcomesinwomenaffectedwithpretermprematureruptureofmembranesanobservationalstudyfromatertiarycarecenterineasternindia