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Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical Publishers, Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246513/ https://www.ncbi.nlm.nih.gov/pubmed/35783028 http://dx.doi.org/10.1055/s-0042-1749423 |
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author | Gupta, Sweety Sharma, Gaurav Sharma, Nidhi Mandal, Shreyosi Gupta, Amit Gupta, Manoj |
author_facet | Gupta, Sweety Sharma, Gaurav Sharma, Nidhi Mandal, Shreyosi Gupta, Amit Gupta, Manoj |
author_sort | Gupta, Sweety |
collection | PubMed |
description | Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented with umbilical mass, but the primary could not be localized even after thorough investigations and work up. Also, there existed therapeutic dilemma because immunohistochemistry did not favor one site, and so he was considered for combination chemotherapy in view of unresectable disease. |
format | Online Article Text |
id | pubmed-9246513 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Thieme Medical Publishers, Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-92465132022-07-01 Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma Gupta, Sweety Sharma, Gaurav Sharma, Nidhi Mandal, Shreyosi Gupta, Amit Gupta, Manoj Surg J (N Y) Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented with umbilical mass, but the primary could not be localized even after thorough investigations and work up. Also, there existed therapeutic dilemma because immunohistochemistry did not favor one site, and so he was considered for combination chemotherapy in view of unresectable disease. Thieme Medical Publishers, Inc. 2022-06-30 /pmc/articles/PMC9246513/ /pubmed/35783028 http://dx.doi.org/10.1055/s-0042-1749423 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Gupta, Sweety Sharma, Gaurav Sharma, Nidhi Mandal, Shreyosi Gupta, Amit Gupta, Manoj Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title | Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title_full | Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title_fullStr | Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title_full_unstemmed | Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title_short | Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma |
title_sort | umbilical nodule metastasis from unknown primary: diagnostic and therapeutic dilemma |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246513/ https://www.ncbi.nlm.nih.gov/pubmed/35783028 http://dx.doi.org/10.1055/s-0042-1749423 |
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