Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma

Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented...

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Autores principales: Gupta, Sweety, Sharma, Gaurav, Sharma, Nidhi, Mandal, Shreyosi, Gupta, Amit, Gupta, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246513/
https://www.ncbi.nlm.nih.gov/pubmed/35783028
http://dx.doi.org/10.1055/s-0042-1749423
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author Gupta, Sweety
Sharma, Gaurav
Sharma, Nidhi
Mandal, Shreyosi
Gupta, Amit
Gupta, Manoj
author_facet Gupta, Sweety
Sharma, Gaurav
Sharma, Nidhi
Mandal, Shreyosi
Gupta, Amit
Gupta, Manoj
author_sort Gupta, Sweety
collection PubMed
description Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented with umbilical mass, but the primary could not be localized even after thorough investigations and work up. Also, there existed therapeutic dilemma because immunohistochemistry did not favor one site, and so he was considered for combination chemotherapy in view of unresectable disease.
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spelling pubmed-92465132022-07-01 Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma Gupta, Sweety Sharma, Gaurav Sharma, Nidhi Mandal, Shreyosi Gupta, Amit Gupta, Manoj Surg J (N Y) Umbilical nodule metastasis is not a common presentation of carcinoma of unknown primary. It may be the presenting symptom of a primary malignancy or as metastatic site of previously diagnosed cancer and is considered to be a poor prognostic finding. We here report a case of young male who presented with umbilical mass, but the primary could not be localized even after thorough investigations and work up. Also, there existed therapeutic dilemma because immunohistochemistry did not favor one site, and so he was considered for combination chemotherapy in view of unresectable disease. Thieme Medical Publishers, Inc. 2022-06-30 /pmc/articles/PMC9246513/ /pubmed/35783028 http://dx.doi.org/10.1055/s-0042-1749423 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Gupta, Sweety
Sharma, Gaurav
Sharma, Nidhi
Mandal, Shreyosi
Gupta, Amit
Gupta, Manoj
Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title_full Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title_fullStr Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title_full_unstemmed Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title_short Umbilical Nodule Metastasis from Unknown Primary: Diagnostic and Therapeutic Dilemma
title_sort umbilical nodule metastasis from unknown primary: diagnostic and therapeutic dilemma
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246513/
https://www.ncbi.nlm.nih.gov/pubmed/35783028
http://dx.doi.org/10.1055/s-0042-1749423
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