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Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?
Limited drug delivery to the brain is one of the major reasons for high failure rates of central nervous system (CNS) drug candidates. The blood–brain barrier (BBB) with its tight junctions, membrane transporters, receptors and metabolizing enzymes is a main player in drug delivery to the brain, res...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246765/ https://www.ncbi.nlm.nih.gov/pubmed/35359241 http://dx.doi.org/10.1007/s11095-022-03241-x |