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Targeting Transporters for Drug Delivery to the Brain: Can We Do Better?

Limited drug delivery to the brain is one of the major reasons for high failure rates of central nervous system (CNS) drug candidates. The blood–brain barrier (BBB) with its tight junctions, membrane transporters, receptors and metabolizing enzymes is a main player in drug delivery to the brain, res...

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Detalles Bibliográficos
Autores principales: Puris, Elena, Fricker, Gert, Gynther, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246765/
https://www.ncbi.nlm.nih.gov/pubmed/35359241
http://dx.doi.org/10.1007/s11095-022-03241-x

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