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Construction and Functional Evaluation of a Three-Dimensional Blood–Brain Barrier Model Equipped With Human Induced Pluripotent Stem Cell-Derived Brain Microvascular Endothelial Cells
PURPOSE: The purpose of this study was to construct and validate an in vitro three-dimensional blood–brain barrier (3DBBB) model system equipped with brain microvascular endothelial cells derived from human induced pluripotent stem cells (hiPS-BMECs). METHODS: The 3D-BBB system was constructed by se...
Autores principales: | Kurosawa, Toshiki, Sako, Daiki, Tega, Yuma, Debori, Yasuyuki, Tomihara, Yumi, Aoyama, Kazunobu, Kubo, Yoshiyuki, Amano, Nobuyuki, Deguchi, Yoshiharu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246774/ https://www.ncbi.nlm.nih.gov/pubmed/35411503 http://dx.doi.org/10.1007/s11095-022-03249-3 |
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