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Stressful life events and trajectories of depression symptoms in a U.S. military cohort
Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly asse...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246834/ https://www.ncbi.nlm.nih.gov/pubmed/35773360 http://dx.doi.org/10.1038/s41598-022-14496-0 |
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author | Sampson, Laura Cabral, Howard J. Rosellini, Anthony J. Gradus, Jaimie L. Cohen, Gregory H. Fink, David S. King, Anthony P. Liberzon, Israel Galea, Sandro |
author_facet | Sampson, Laura Cabral, Howard J. Rosellini, Anthony J. Gradus, Jaimie L. Cohen, Gregory H. Fink, David S. King, Anthony P. Liberzon, Israel Galea, Sandro |
author_sort | Sampson, Laura |
collection | PubMed |
description | Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a “chronic” symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse—not only those from deployment—when studying the mental health of servicemembers. |
format | Online Article Text |
id | pubmed-9246834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92468342022-07-02 Stressful life events and trajectories of depression symptoms in a U.S. military cohort Sampson, Laura Cabral, Howard J. Rosellini, Anthony J. Gradus, Jaimie L. Cohen, Gregory H. Fink, David S. King, Anthony P. Liberzon, Israel Galea, Sandro Sci Rep Article Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a “chronic” symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse—not only those from deployment—when studying the mental health of servicemembers. Nature Publishing Group UK 2022-06-30 /pmc/articles/PMC9246834/ /pubmed/35773360 http://dx.doi.org/10.1038/s41598-022-14496-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Sampson, Laura Cabral, Howard J. Rosellini, Anthony J. Gradus, Jaimie L. Cohen, Gregory H. Fink, David S. King, Anthony P. Liberzon, Israel Galea, Sandro Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title | Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title_full | Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title_fullStr | Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title_full_unstemmed | Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title_short | Stressful life events and trajectories of depression symptoms in a U.S. military cohort |
title_sort | stressful life events and trajectories of depression symptoms in a u.s. military cohort |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246834/ https://www.ncbi.nlm.nih.gov/pubmed/35773360 http://dx.doi.org/10.1038/s41598-022-14496-0 |
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