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Stressful life events and trajectories of depression symptoms in a U.S. military cohort

Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly asse...

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Autores principales: Sampson, Laura, Cabral, Howard J., Rosellini, Anthony J., Gradus, Jaimie L., Cohen, Gregory H., Fink, David S., King, Anthony P., Liberzon, Israel, Galea, Sandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246834/
https://www.ncbi.nlm.nih.gov/pubmed/35773360
http://dx.doi.org/10.1038/s41598-022-14496-0
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author Sampson, Laura
Cabral, Howard J.
Rosellini, Anthony J.
Gradus, Jaimie L.
Cohen, Gregory H.
Fink, David S.
King, Anthony P.
Liberzon, Israel
Galea, Sandro
author_facet Sampson, Laura
Cabral, Howard J.
Rosellini, Anthony J.
Gradus, Jaimie L.
Cohen, Gregory H.
Fink, David S.
King, Anthony P.
Liberzon, Israel
Galea, Sandro
author_sort Sampson, Laura
collection PubMed
description Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a “chronic” symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse—not only those from deployment—when studying the mental health of servicemembers.
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spelling pubmed-92468342022-07-02 Stressful life events and trajectories of depression symptoms in a U.S. military cohort Sampson, Laura Cabral, Howard J. Rosellini, Anthony J. Gradus, Jaimie L. Cohen, Gregory H. Fink, David S. King, Anthony P. Liberzon, Israel Galea, Sandro Sci Rep Article Depression is a common mental disorder that may comprise distinct, underlying symptom patterns over time. Associations between stressful life events throughout the civilian lifecourse—including during childhood—and adult depression have been documented in many populations, but are less commonly assessed in military samples. We identified different trajectories of depression symptoms across four years in a military cohort using latent class growth analysis, and investigated the relationship between these trajectories and two domains of civilian life experiences: childhood adversity (e.g., being mistreated during childhood) and more proximal stressful experiences (e.g., divorce). A four-group depression model was identified, including a symptom-free group (62%), an increasing symptom group (13%), a decreasing symptom group (16%), and a “chronic” symptom group (9%). Compared to the symptom-free group, soldiers with childhood adversity were more likely to be in the chronic depression, decreasing, and increasing symptom groups. Time-varying adult stressors had the largest effect on depression symptoms for the increasing symptom group compared to other groups, particularly in the last two years of follow-up. This study indicates the importance of considering events from throughout the lifecourse—not only those from deployment—when studying the mental health of servicemembers. Nature Publishing Group UK 2022-06-30 /pmc/articles/PMC9246834/ /pubmed/35773360 http://dx.doi.org/10.1038/s41598-022-14496-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Sampson, Laura
Cabral, Howard J.
Rosellini, Anthony J.
Gradus, Jaimie L.
Cohen, Gregory H.
Fink, David S.
King, Anthony P.
Liberzon, Israel
Galea, Sandro
Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title_full Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title_fullStr Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title_full_unstemmed Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title_short Stressful life events and trajectories of depression symptoms in a U.S. military cohort
title_sort stressful life events and trajectories of depression symptoms in a u.s. military cohort
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246834/
https://www.ncbi.nlm.nih.gov/pubmed/35773360
http://dx.doi.org/10.1038/s41598-022-14496-0
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