N(6)-methyladenosine methylation-regulated polo-like kinase 1 cell cycle homeostasis as a potential target of radiotherapy in pancreatic adenocarcinoma

In pancreatic cancer, methyltransferase-like 3 (METTL3), a N(6)-methyladenosine (m6A) methyltransferase, has a favorable effect on tumors and is a risk factor for patients’ prognosis. However, the details of what genes are regulated by METTL3 remain unknown. Several RNAs are methylated, and what gen...

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Detalles Bibliográficos
Autores principales: Tatekawa, Shotaro, Tamari, Keisuke, Chijimatsu, Ryota, Konno, Masamitsu, Motooka, Daisuke, Mitsufuji, Suguru, Akita, Hirofumi, Kobayashi, Shogo, Murakumo, Yoshiki, Doki, Yuichiro, Eguchi, Hidetoshi, Ishii, Hideshi, Ogawa, Kazuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246847/
https://www.ncbi.nlm.nih.gov/pubmed/35773310
http://dx.doi.org/10.1038/s41598-022-15196-5

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