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Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study

The purpose of this study is to evaluate the relationship between preoperative physical performance (grip strength, gait speed, timed up and go) and postoperative pulmonary complications (PPCs) in patients who have undergone coronary artery bypass grafting (CABG). From September 2019 to August 2021,...

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Autores principales: Li, Lin, Yang, Qin, Guo, Qi, Liu, Dandan, Gao, Hui, Liu, Yaping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246884/
https://www.ncbi.nlm.nih.gov/pubmed/35773331
http://dx.doi.org/10.1038/s41598-022-15145-2
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author Li, Lin
Yang, Qin
Guo, Qi
Liu, Dandan
Gao, Hui
Liu, Yaping
author_facet Li, Lin
Yang, Qin
Guo, Qi
Liu, Dandan
Gao, Hui
Liu, Yaping
author_sort Li, Lin
collection PubMed
description The purpose of this study is to evaluate the relationship between preoperative physical performance (grip strength, gait speed, timed up and go) and postoperative pulmonary complications (PPCs) in patients who have undergone coronary artery bypass grafting (CABG). From September 2019 to August 2021, a total of 497 CABG patients who met the inclusion criteria of this study were examined for grip strength, 4-m gait speed, and timed up and go (TUG) before CABG surgery. Among them, 438 were included in the final analysis. PPCs were classified according to the operational definition of Kroenke et al. and patients with clinically significant PPCs were included in the data analysis. Logistic regression was utilised to analyse the relationship between physical performance and clinically significant PPCs. Besides, the receiver operating characteristic (ROC) curve was applied to analyse the predictive effect of grip strength, gait speed, and TUG on clinically significant PPCs after the CABG procedure. In total, 103 (23.5%) patients developed clinically significant PPCs after CABG. After making adjustments for the European System for Cardiac Operative Risk Evaluation (EuroSCORE) and confounding factors, we established that low grip/weight (OR 0.510; 95% CI 0.363–0.715), slow gait speed (OR 0.619; 95% CI 0.517–0.741), and prolonged TUG (OR 1.617; 95% CI 1.379–1.895) were all independently correlated with clinically significant PPCs after CABG. The ROC curve analysis indicated that the area under the ROC curve of the integrated model of the three indicators (AUC 0.792 vs. 0.682, 0.754, 0.765) was larger than that of the model with a single indicator. Besides the predictive effect of the integrated model was superior to the models using grip/weight, gait speed, or TUG alone. Physical performance, including grip/weight, gait speed, and TUG, is a predictive factor for PPCs in CABG patients, and can be used in preoperative evaluations to and help improve the management of high-risk patients.
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spelling pubmed-92468842022-07-02 Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study Li, Lin Yang, Qin Guo, Qi Liu, Dandan Gao, Hui Liu, Yaping Sci Rep Article The purpose of this study is to evaluate the relationship between preoperative physical performance (grip strength, gait speed, timed up and go) and postoperative pulmonary complications (PPCs) in patients who have undergone coronary artery bypass grafting (CABG). From September 2019 to August 2021, a total of 497 CABG patients who met the inclusion criteria of this study were examined for grip strength, 4-m gait speed, and timed up and go (TUG) before CABG surgery. Among them, 438 were included in the final analysis. PPCs were classified according to the operational definition of Kroenke et al. and patients with clinically significant PPCs were included in the data analysis. Logistic regression was utilised to analyse the relationship between physical performance and clinically significant PPCs. Besides, the receiver operating characteristic (ROC) curve was applied to analyse the predictive effect of grip strength, gait speed, and TUG on clinically significant PPCs after the CABG procedure. In total, 103 (23.5%) patients developed clinically significant PPCs after CABG. After making adjustments for the European System for Cardiac Operative Risk Evaluation (EuroSCORE) and confounding factors, we established that low grip/weight (OR 0.510; 95% CI 0.363–0.715), slow gait speed (OR 0.619; 95% CI 0.517–0.741), and prolonged TUG (OR 1.617; 95% CI 1.379–1.895) were all independently correlated with clinically significant PPCs after CABG. The ROC curve analysis indicated that the area under the ROC curve of the integrated model of the three indicators (AUC 0.792 vs. 0.682, 0.754, 0.765) was larger than that of the model with a single indicator. Besides the predictive effect of the integrated model was superior to the models using grip/weight, gait speed, or TUG alone. Physical performance, including grip/weight, gait speed, and TUG, is a predictive factor for PPCs in CABG patients, and can be used in preoperative evaluations to and help improve the management of high-risk patients. Nature Publishing Group UK 2022-06-30 /pmc/articles/PMC9246884/ /pubmed/35773331 http://dx.doi.org/10.1038/s41598-022-15145-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Li, Lin
Yang, Qin
Guo, Qi
Liu, Dandan
Gao, Hui
Liu, Yaping
Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title_full Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title_fullStr Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title_full_unstemmed Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title_short Preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
title_sort preoperative physical performance predicts pulmonary complications after coronary artery bypass grafting: a prospective study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246884/
https://www.ncbi.nlm.nih.gov/pubmed/35773331
http://dx.doi.org/10.1038/s41598-022-15145-2
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