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Occlusion of dopamine-dependent synaptic plasticity in the prefrontal cortex mediates the expression of depressive-like behavior and is modulated by ketamine

Unpredictable chronic mild stress (CMS) is among the most popular protocols used to induce depressive-like behaviors such as anhedonia in rats. Differences in CMS protocols often result in variable degree of vulnerability, and the mechanisms behind stress resilience are of great interest in neurosci...

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Detalles Bibliográficos
Autores principales: Lamanna, Jacopo, Isotti, Francesco, Ferro, Mattia, Spadini, Sara, Racchetti, Gabriella, Musazzi, Laura, Malgaroli, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246912/
https://www.ncbi.nlm.nih.gov/pubmed/35773275
http://dx.doi.org/10.1038/s41598-022-14694-w