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Occlusion of dopamine-dependent synaptic plasticity in the prefrontal cortex mediates the expression of depressive-like behavior and is modulated by ketamine
Unpredictable chronic mild stress (CMS) is among the most popular protocols used to induce depressive-like behaviors such as anhedonia in rats. Differences in CMS protocols often result in variable degree of vulnerability, and the mechanisms behind stress resilience are of great interest in neurosci...
Autores principales: | Lamanna, Jacopo, Isotti, Francesco, Ferro, Mattia, Spadini, Sara, Racchetti, Gabriella, Musazzi, Laura, Malgaroli, Antonio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246912/ https://www.ncbi.nlm.nih.gov/pubmed/35773275 http://dx.doi.org/10.1038/s41598-022-14694-w |
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