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Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0

Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration of the relation between genotype and phenotype. Streamlined integration of enzyme constraints and proteomics data into such models was first enabled by the GECKO toolbox, allowing the study of phenotypes constrai...

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Detalles Bibliográficos
Autores principales: Domenzain, Iván, Sánchez, Benjamín, Anton, Mihail, Kerkhoven, Eduard J., Millán-Oropeza, Aarón, Henry, Céline, Siewers, Verena, Morrissey, John P., Sonnenschein, Nikolaus, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246944/
https://www.ncbi.nlm.nih.gov/pubmed/35773252
http://dx.doi.org/10.1038/s41467-022-31421-1