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Reconstruction of a catalogue of genome-scale metabolic models with enzymatic constraints using GECKO 2.0
Genome-scale metabolic models (GEMs) have been widely used for quantitative exploration of the relation between genotype and phenotype. Streamlined integration of enzyme constraints and proteomics data into such models was first enabled by the GECKO toolbox, allowing the study of phenotypes constrai...
Autores principales: | Domenzain, Iván, Sánchez, Benjamín, Anton, Mihail, Kerkhoven, Eduard J., Millán-Oropeza, Aarón, Henry, Céline, Siewers, Verena, Morrissey, John P., Sonnenschein, Nikolaus, Nielsen, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9246944/ https://www.ncbi.nlm.nih.gov/pubmed/35773252 http://dx.doi.org/10.1038/s41467-022-31421-1 |
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